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Metals—Lead

2003· book-chapter· en· W4388361008 on OpenAlexaff
Donald T. Wigle

Bibliographic record

Venuenot available
Typebook-chapter
Languageen
FieldEnvironmental Science
TopicHeavy Metal Exposure and Toxicity
Canadian institutionsInstitute of Population and Public HealthUniversity of Ottawa
Fundersnot available
KeywordsLead poisoningLead exposureLead (geology)Environmental healthContaminated foodMedicineAdverse effectToxicologyEnvironmental scienceBiology

Abstract

fetched live from OpenAlex

Abstract The twentieth century saw greatly expanded use and environmental dispersion of lead, a dense metal valued since antiquity because of its low melting point, pliability, and durability. Analysis of a Swiss peat bog showed that annual average lead deposition increased 1600-fold between 5000 B.C. and the maximum in 1979. Recognition of adult lead poisoning with abdominal colic can be traced to Hippocrates in about 370 B.C. (in metal workers) and Baker in 1767 (who linked Devonshire colic to consumption of lead-contaminated cider) (Table 4–1). Childhood lead poisoning was recognized as a distinct entity in 1892 and neurotoxicity in experimental animals by the 1920s. There has been substantial progress in reducing childhood lead exposure, but many children remain at risk. The objective of this chapter is to illustrate how failure to apply the precautionary principle allowed inappropriate uses of lead, massive environmental contamination, and major adverse impacts on child health. The first section focuses mainly on the susceptibility of the developing human nervous system to adverse neurobehavioral effects from relatively low-level lead exposure, as evidenced by epidemiologic and toxicologic studies. The discussion includes environmental indices and biomarkers of lead exposure and toxico-kinetics. The risk management section addresses lead sources (air, water, food, soil/dust) and interventions for preventing childhood lead exposure.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.054
Threshold uncertainty score0.180

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0540.041

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.223
Teacher spread0.200 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2003
Admission routes1
Has abstractyes

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