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Record W4388365687 · doi:10.1016/j.ibneur.2023.08.064

CA2+ IMAGING OF SELF AND OTHER IN MEDIAL PREFRONTAL CORTEX DURING SOCIAL DOMINANCE INTERACTIONS IN A TUBE-TEST

2023· article· en· W4388365687 on OpenAlexaff
Núria Marcó García, Rufus Mitchell‐Heggs, Kapil Saxena, Sumantra Chattarji, Peter C. Kind, Simon R. Schultz, Richard Morris

Bibliographic record

VenueIBRO Neuroscience Reports · 2023
Typearticle
Languageen
FieldPsychology
TopicNeuroendocrine regulation and behavior
Canadian institutionsDiscovery Centre
Fundersnot available
KeywordsPrefrontal cortexSelf-reference effectConsumer neuroscienceNeurosciencePsychologyDominance (genetics)BiologyCognition

Abstract

fetched live from OpenAlex

Obesity is a growing problem worldwide with significant health, educational, and social impact.Early experiences play a decisive role in shaping adult behavior.While it is known that maternal obesity can determine offspring's predisposition to overweight, heart disease, diabetes, or hypertension, it is still yet unclear how it affects eating behavior and diet selection.It can be foreseen that prenatal exposure to high-calorie diets can be expected to develop postnatal taste preferences and/or changes in the reinforcing value of sweet taste leading to increased intake of sweets and fats, thus having a causal role in obesity.This issue is especially important during adolescence, a critical and peculiar period that will largely determine subsequent adult performance.Understanding the effect of Western diets (high-fat and high-sugar diets), during early development on the formation of taste preferences may be critical to fight against this global pandemic.In this experimental series, four groups of pregnant female Wistar rats were fed different diets (high sucrose and fat; high sucrose; high fat or standard) for one month before mating and throughout gestation.Offspring taste preferences were evaluated during adolescence in addition to a battery of behavioral tests including spontaneous exploration, and spatial memory.Offspring from mothers fed Western diets accepted low concentration and rejected high concentrations of sucrose solutions.This is consistent with lower weight in this group, supporting better eating behavior regulation.These results suggest that prenatal influences can shape long-term preferences and may have beneficial effects on diet selection and caloric management.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.286
Threshold uncertainty score0.415

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.349
Teacher spread0.323 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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