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Record W4388373624 · doi:10.1101/2023.11.05.565682

Cortical areas for planning sequences before and during movement

2023· preprint· en· W4388373624 on OpenAlexafffund
Giacomo Ariani, Mahdiyar Shahbazi, Jörn Diedrichsen

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2023
Typepreprint
Languageen
FieldNeuroscience
TopicFunctional Brain Connectivity Studies
Canadian institutionsWestern University
FundersNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health ResearchCanada First Research Excellence Fund
KeywordsSomatosensory systemMotor planningMovement (music)Motor areaNeuroscienceSequence (biology)BiologyPhysical medicine and rehabilitationMedicineGenetics

Abstract

fetched live from OpenAlex

Production of rapid movement sequences relies on preparation before (pre-planning) and during (online planning) movement. Here, we asked how different cortical sensorimotor areas contribute to these processes. Human participants performed three single-finger and three multi-finger sequences in a delayed movement paradigm. During preparation, 7T functional MRI revealed that primary motor (M1) and somatosensory (S1) areas showed pre-activation of the first movement, even though the overall activation level did not change from baseline. During production, the activity in M1 and S1 could be explained by temporal summation of activity patterns corresponding to constituent fingers. In contrast, dorsal premotor (PMd) and anterior superior parietal lobule (aSPL) showed substantial activation during preparation of multi-finger as compared to single-finger sequences. The same regions were also more activated during production of multi-finger sequences, suggesting that the same areas are involved in both pre- and online planning. Nonetheless, we observed small but robust differences between the two contrasts, suggesting preferential involvements of these areas in pre- and online planning. Multivariate analysis revealed sequence-specific representations in both PMd and aSPL, which remained stable across both preparation and production phases. This suggests that these areas maintain a sequence-specific representation before and during sequence production, likely guiding the execution-related areas.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.264
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2023
Admission routes2
Has abstractyes

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