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Record W4388398535 · doi:10.1002/ardp.202300610

Gunda Georg receives Carl Mannich medal

2023· editorial· en· W4388398535 on OpenAlex
Wibke E. Diederich, Andreas Link

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueArchiv der Pharmazie · 2023
Typeeditorial
Languageen
FieldChemistry
TopicClick Chemistry and Applications
Canadian institutionsnot available
Fundersnot available
KeywordsMarburg virusChemistryLibrary sciencePhilosophyMedicineComputer scienceVirology

Abstract

fetched live from OpenAlex

The Deutsche Pharmazeutische Gesellschaft (DPhG) has awarded our editorial advisory board member Prof. Dr. Gunda Georg the Carl Mannich medal 2023 for her outstanding achievements in the field of pharmaceutical sciences (Figure 1). Prof. Georg's scientific career began at the Philipps University of Marburg, where she studied pharmacy and obtained her doctorate in pharmaceutical chemistry under the supervision of Prof. Dr. Manfred Haake in 1980. After a postdoctoral fellowship at the University of Ottawa in Prof. Tony Durst's group and an appointment as Assistant Professor of Medicinal Chemistry at the University of Rhode Island, she joined the Department of Medicinal Chemistry at the University of Kansas in 1984, where she was named University Distinguished Professor in 1999. Since 2007, Prof. Dr. Georg continues to be Regents Professor at the Department of Medicinal Chemistry at the University of Minnesota and Director of the Institute for Therapeutics Discovery and Development as well as holder of the “Robert Vince Endowed Chair” and the “McKnight Presidential Chair in Medicinal Chemistry” with very great success until today. The results of her more than 40 years of research have been published in more than 250 original papers, two of them were recently published in our journal,[1, 2] and patents and have established her reputation as a world leader in medicinal chemistry. Particularly noteworthy is her work on the cancer therapeutics paclitaxel, the epothilones, and crypthophycins. She is coinventor of Lusedra®, which was marketed by Eisa Pharmaceuticals, and Minnelide®, an anticancer agent in Phase II clinical trials. Her current research areas include nonhormonal contraceptives for men[1] and women. She is co-inventor of YCT529, a selective retinoic acid receptor alpha antagonist that has been licensed by Your Choice Therapeutics and is scheduled for clinical trials in 2023. It will be the first nonhormonal male contraceptive to enter clinical trials. BBC Science Focus listed the discovery of YCT529 as #1 of the 19 most amazing science stories of 2022.[3] In her long research career, Prof. Dr. Georg has supervised and always supported more than 100 PhD students and postdocs with great commitment. In addition to the Carl Mannich medal of the German Pharmaceutical Society, she has received numerous other awards and prizes, of which only a few are mentioned here as representatives: In 2017, she was inducted into the Hall of Fame of the Division of Medicinal Chemistry of the American Chemical Society. In 2020, she became the first woman ever to receive the Alfred Burger Award in Medicinal Chemistry, one of the most prestigious awards in medicinal chemistry, for her outstanding achievements in the field. She was co-Editor-in-Chief of the Journal of Medicinal Chemistry from 2012 to 2020 and joined the Advisory Board of the Archiv der Pharmazie in 2021. We thank you very much for your continuous support of the Archiv and congratulate you, dear Gunda, very warmly on the award of the Carl Mannich medal. Wibke and Andreas

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.095
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.318
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it