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Record W4388398535 · doi:10.1002/ardp.202300610

Gunda Georg receives Carl Mannich medal

2023· editorial· en· W4388398535 on OpenAlexaboutno aff
Wibke E. Diederich, Andreas Link

Bibliographic record

VenueArchiv der Pharmazie · 2023
Typeeditorial
Languageen
FieldChemistry
TopicClick Chemistry and Applications
Canadian institutionsnot available
Fundersnot available
KeywordsMarburg virusChemistryLibrary sciencePhilosophyMedicineComputer scienceVirology

Abstract

fetched live from OpenAlex

The Deutsche Pharmazeutische Gesellschaft (DPhG) has awarded our editorial advisory board member Prof. Dr. Gunda Georg the Carl Mannich medal 2023 for her outstanding achievements in the field of pharmaceutical sciences (Figure 1). Prof. Georg's scientific career began at the Philipps University of Marburg, where she studied pharmacy and obtained her doctorate in pharmaceutical chemistry under the supervision of Prof. Dr. Manfred Haake in 1980. After a postdoctoral fellowship at the University of Ottawa in Prof. Tony Durst's group and an appointment as Assistant Professor of Medicinal Chemistry at the University of Rhode Island, she joined the Department of Medicinal Chemistry at the University of Kansas in 1984, where she was named University Distinguished Professor in 1999. Since 2007, Prof. Dr. Georg continues to be Regents Professor at the Department of Medicinal Chemistry at the University of Minnesota and Director of the Institute for Therapeutics Discovery and Development as well as holder of the “Robert Vince Endowed Chair” and the “McKnight Presidential Chair in Medicinal Chemistry” with very great success until today. The results of her more than 40 years of research have been published in more than 250 original papers, two of them were recently published in our journal,[1, 2] and patents and have established her reputation as a world leader in medicinal chemistry. Particularly noteworthy is her work on the cancer therapeutics paclitaxel, the epothilones, and crypthophycins. She is coinventor of Lusedra®, which was marketed by Eisa Pharmaceuticals, and Minnelide®, an anticancer agent in Phase II clinical trials. Her current research areas include nonhormonal contraceptives for men[1] and women. She is co-inventor of YCT529, a selective retinoic acid receptor alpha antagonist that has been licensed by Your Choice Therapeutics and is scheduled for clinical trials in 2023. It will be the first nonhormonal male contraceptive to enter clinical trials. BBC Science Focus listed the discovery of YCT529 as #1 of the 19 most amazing science stories of 2022.[3] In her long research career, Prof. Dr. Georg has supervised and always supported more than 100 PhD students and postdocs with great commitment. In addition to the Carl Mannich medal of the German Pharmaceutical Society, she has received numerous other awards and prizes, of which only a few are mentioned here as representatives: In 2017, she was inducted into the Hall of Fame of the Division of Medicinal Chemistry of the American Chemical Society. In 2020, she became the first woman ever to receive the Alfred Burger Award in Medicinal Chemistry, one of the most prestigious awards in medicinal chemistry, for her outstanding achievements in the field. She was co-Editor-in-Chief of the Journal of Medicinal Chemistry from 2012 to 2020 and joined the Advisory Board of the Archiv der Pharmazie in 2021. We thank you very much for your continuous support of the Archiv and congratulate you, dear Gunda, very warmly on the award of the Carl Mannich medal. Wibke and Andreas

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: none
Teacher disagreement score0.637
Threshold uncertainty score0.517

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0020.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0040.002
Open science0.0010.003
Research integrity0.0040.003
Insufficient payload (model declined to judge)0.6370.515

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.318
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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