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Record W4388500089 · doi:10.1038/s44184-023-00044-9

Managing expectations with psychedelic microdosing

2023· letter· en· W4388500089 on OpenAlexaff
Omer A. Syed, Benjamin Tsang

Bibliographic record

Venuenpj Mental Health Research · 2023
Typeletter
Languageen
FieldPsychology
TopicPsychedelics and Drug Studies
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsPsychologyRecreationRecreational useMental healthApplied psychologyPsychotherapistPolitical science

Abstract

fetched live from OpenAlex

The recent years have seen an unprecedented surge of psychedelic research. Studies with psilocybin (colloquially known as magic mushrooms), in particular, have shown promise in ameliorating symptoms of treatment-refractory depression, anxiety, and substance use disorder, among others 1 , 2 . Microdosing, the practice of regularly taking roughly a tenth of full psychedelic doses, is becoming increasingly popular 3 . These sub-perceptual doses cause no psychedelic effects, yet anecdotal reports suggest they carry substantial improvements to mental wellbeing. Popularized in-part by Silicon Valley developers and entrepreneurs, microdosing psilocybin and LSD is widely suggested to boost creativity, attention, sociability, while treating low mood and anxiety. Additionally, recent years have seen microdosing permeating the mainstream psychedelic scene. Several recent self-report survey studies demonstrate the overwhelming positive effects of microdosing on users’ mental health 3 , 4 .

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.127
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0020.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.004
Insufficient payload (model declined to judge)0.0000.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.386
GPT teacher head0.557
Teacher spread0.171 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2023
Admission routes1
Has abstractyes

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