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Record W4388539569 · doi:10.1161/strokeaha.123.044985

Priorities for Advancements in Neuroimaging in the Diagnostic Workup of Acute Stroke

2023· review· en· W4388539569 on OpenAlexaff
Edgar A. Samaniego, Johannes Boltze, Patrick D. Lyden, Michael D. Hill, Bruce Campbell, Gisele Sampaio Silva, Kevin N. Sheth, Marc Fisher, Argye E. Hillis, Thanh N. Nguyen, Davide Carone, Christopher G. Favilla, Emir Deljkich, Gregory W. Albers, Jeremy J. Heit, Maarten G. Lansberg, Didem Aksoy, Joe Broderick, Alicia C. Castonguay, Supurna Ghosh, James C. Grotta, George Harston, Gary Houser, Kristopher Kuchenbecker, Lawrence L. Latour, David S Liebeskind, John Kylan Lynch, Carolina M. Maier, Eva Mistry, J Mocco, Raul G. Nogueira, Jeffrey L. Saver, Marijke van Vlimmeren, Ajay K. Wakhloo, Lawrence R. Wechsler

Bibliographic record

VenueStroke · 2023
Typereview
Languageen
FieldMedicine
TopicAcute Ischemic Stroke Management
Canadian institutionsFoothills Medical Centre
FundersNational Center for Advancing Translational SciencesNational Institute of Neurological Disorders and StrokeNational Institutes of HealthIdorsia Pharmaceuticals
KeywordsMedicineNeuroimagingThrombolysisStroke (engine)Acute strokeMedical imagingRadiologyIntensive care medicineMedical physicsTissue plasminogen activatorCardiologyInternal medicineMyocardial infarctionPsychiatry

Abstract

fetched live from OpenAlex

STAIR XII (12th Stroke Treatment Academy Industry Roundtable) included a workshop to discuss the priorities for advancements in neuroimaging in the diagnostic workup of acute ischemic stroke. The workshop brought together representatives from academia, industry, and government. The participants identified 10 critical areas of priority for the advancement of acute stroke imaging. These include enhancing imaging capabilities at primary and comprehensive stroke centers, refining the analysis and characterization of clots, establishing imaging criteria that can predict the response to reperfusion, optimizing the Thrombolysis in Cerebral Infarction scale, predicting first-pass reperfusion outcomes, improving imaging techniques post-reperfusion therapy, detecting early ischemia on noncontrast computed tomography, enhancing cone beam computed tomography, advancing mobile stroke units, and leveraging high-resolution vessel wall imaging to gain deeper insights into pathology. Imaging in acute ischemic stroke treatment has advanced significantly, but important challenges remain that need to be addressed. A combined effort from academic investigators, industry, and regulators is needed to improve imaging technologies and, ultimately, patient outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.008
Threshold uncertainty score0.045

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.006
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0040.003
Science and technology studies0.0010.001
Scholarly communication0.0030.004
Open science0.0010.002
Research integrity0.0040.005
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.376
Teacher spread0.314 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations18
Published2023
Admission routes1
Has abstractyes

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