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Record W4389001951 · doi:10.1101/2023.11.23.568508

Stimulating prefrontal cortex facilitates training transfer by increasing representational overlap

2023· preprint· en· W4389001951 on OpenAlexaff
Yohan Wards, Shane E. Ehrhardt, Hannah L. Filmer, Jason B. Mattingley, Kelly Garner, Paul E. Dux

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2023
Typepreprint
Languageen
FieldNeuroscience
TopicNeural and Behavioral Psychology Studies
Canadian institutionsCanadian Institute for Advanced Research
FundersNational Health and Medical Research CouncilEuropean CommissionMedical Research CouncilAustralian Government
KeywordsHuman multitaskingTranscranial direct-current stimulationPrefrontal cortexTask (project management)PsychologyCognitive psychologyNeuroscienceFunctional magnetic resonance imagingPosterior parietal cortexTranscranial magnetic stimulationComputer scienceStimulationCognition

Abstract

fetched live from OpenAlex

Abstract Difficulties in multitasking may be the price humans pay for our ability to generalise learning to new tasks. Mitigating these costs through training has been associated with reduced overlap of constituent task representations within a task-related brain network. Transcranial direct current stimulation (tDCS), which can modulate neural activity, has shown promise in generalising training gains. Whether tDCS influences the changes in task-associated representations to produce such training generalisation remains unexplored. Here, we paired prefrontal cortex tDCS with multitasking training, and collected functional magnetic resonance imaging data pre- and post- training. We found that 1mA tDCS enhanced visual search performance, and using machine learning to assess the overlap of brain activity related to the training, show that these generalised gains were predicted by changes in classification accuracy for patterns of frontal, parietal, and cerebellar activity in participants who received left prefrontal cortex stimulation. Thus, prefrontal cortex tDCS interacts with training related changes in task representations, potentially driving the generalisation of learning.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.128
GPT teacher head0.325
Teacher spread0.197 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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