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Record W4389083699 · doi:10.1111/bjh.19214

Early liver complications after allogeneic haematopoietic stem cell transplantation in patients with myelofibrosis: A study on behalf of the Chronic Malignancies Working Party of the <scp>EBMT</scp>

2023· letter· en· W4389083699 on OpenAlexaboutno aff
Marie Robin, Luuk Gras, Linda Köster, Nico Gagelmann, Gwendolyn Van Gorkom, Matthias Ederr, Maija Itälä‐Remes, Tsila Zuckerman, Yves Béguin, Nicolaas Schaap, Joanna Drozd‐Sokołowska, Kavita Raj, Patrick Hayden, Liesbeth C. de Wreede, Giorgia Battipaglia, Nicola Polverelli, Tomasz Czerw, Juan Carlos Hernández‐Boluda, Nicolaus Kröger, Ibrahim Yakoub‐Agha, Donal P. McLornan

Bibliographic record

VenueBritish Journal of Haematology · 2023
Typeletter
Languageen
FieldMedicine
TopicChronic Myeloid Leukemia Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMyelofibrosisHaematopoiesisStem cellMedicineTransplantationHematopoietic stem cell transplantationInternal medicineOncologyBiologyBone marrow

Abstract

fetched live from OpenAlex

Outcome after HSCT, (A-E): probability of overall survival (OS) by (A) liver AE grade, (B) age at HSCT (years), (C) HCT-CI risk category, (D) type of disease, (E) type of donor and (F-J): cumulative incidence of non-relapse mortality (NRM) by (F) liver AE grade, (G) liver AE + organ involvement, (H) bilirubin toxicity, (I) iatrogenic liver AE (as reported on questionnaire) and (J) type of donor.Figure (A) and (F-I) are landmark analyses starting from 100 days after HSCT, all other figures start from HSCT.Numbers below the graphs show the number at risk.Shaded areas show the 95% confidence intervals.p-values were obtained using the log-rank test from figure (A-E) and Gray's test for Figure (F-J).high, HCT-CI risk score 3 or more; HSCT, haematopoietic stem cell transplantation; Intermediate, HCT CI risk score 1-2; low, HCT-CI risk score 0; MMUD, mismatched unrelated donor; MUD, matched unrelated donor; pMF, primary myelofibrosis; sMF, secondary myelofibrosis; tAML, transformed to AML.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.220
Teacher spread0.204 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes1
Has abstractyes

Explore more

Same venueBritish Journal of HaematologySame topicChronic Myeloid Leukemia TreatmentsFrench-language works237,207