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A Randomized Control Trial to Assess the Efficacy and Safety of Manna Go Grains to Promote Growth, Immunity, and Well-Being in Children

2023· article· en· W4389236529 on OpenAlexvenueno aff
Murugan Narayanaswamy, B. Divya, Rahul More, Navnath Jadhav, Gayatri Ganu

Bibliographic record

VenueInternational Journal of Child Health and Nutrition · 2023
Typearticle
Languageen
FieldNursing
TopicChild Nutrition and Water Access
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineImmunityRandomized controlled trialAppetiteMicronutrientInternal medicineImmunologyImmune system

Abstract

fetched live from OpenAlex

Objective: Nutrition in school-going children is crucial for their lifetime. India witnesses macro and micronutrient deficiencies in school-going children. The present study aims to evaluate the safety and efficacy of Manna go grains in promoting and improving growth, immunity, and well-being in children. Method: This was a 90-day randomized, controlled, parallel-arm clinical trial. 6-12 years old apparently healthy sixty-two children were randomized either into a test (Manna go grains plus milk) or a control group (milk) in a 1:1 ratio. We assessed changes in growth, immunity, appetite, and overall well-being before and after treatment. Result: The test group showed a significant increase in height, weight, height to age, and weight to age Z score and percentile, which was greater than the control group. There was significantly more improvement in VO2 max and appetite of children in the test group was observed as compared to the control group. A significant reduction in recurrent URTI episodes, sick days, recovery days, and missed school days was observed in the test group compared to the control. Memory questionnaire scores also increased significantly by 75% and 27.61% in the test and control groups. Test group parents reported significantly better growth, stamina, and immunity than the control group. There was clinically and statistically insignificant change in CBC, serum iron, serum calcium, and immunity markers like CD3, CD4, CD8, and IgG in both groups. Conclusion: Thus, Manna Go grains are thought to be a good candidate as a supplement for potentially stimulating growth and development in children and promoting their well-being.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.033

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.005
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0050.002
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0010.001
Open science0.0020.001
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0100.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.328
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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