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Record W4389279230 · doi:10.33140/tapi.06.01.14

The Successful Launch and Diffusion of New Therapies

2023· article· en· W4389279230 on OpenAlexfundno aff
Rehan Author, Rehan Haider

Bibliographic record

VenueToxicology and Applied Pharmacology Insights · 2023
Typearticle
Languageen
FieldEconomics, Econometrics and Finance
TopicPharmaceutical Economics and Policy
Canadian institutionsnot available
FundersUniversity of KarachiUniversity of Calgary
KeywordsPromotion (chess)Risk analysis (engineering)Pharmaceutical industryBusinessValue (mathematics)Field (mathematics)MarketingManagement scienceProcess managementComputer scienceEngineeringBiotechnology

Abstract

fetched live from OpenAlex

The successful launch and diffusion of new drugs is an essential factor for the survival of many pharmaceutical firms. To ensure the success of a new drug, sophisticated managers in this industry require decision-support tools. This review presents an overview of such strategic and analytical tools, based on significant contributions by marketing scientists. The review is organized according to the components of a launch and diffusion decision chain which represents the sequence of decisions that must be made when launching a new drug. This includes methods for gauging the commercial potential of a new treatment over time, pricing and promotion strategies to maximize value, and leveraging potential across different countries. This review provides an overview of current methods and possible directions for future advances in the field. The successful launch and diffusion of new therapies are key factors in the success of pharmaceutical firms. To ensure the success of a new drug, sophisticated managers in this industry require decision-support tools. This review provides an overview of such strategic and analytical tools, based on significant contributions by marketing scientists. This includes methods for gauging the commercial potential of a new treatment over time, pricing and promotion strategies to maximize value, and leveraging potential across different countries. This review is organized according to the components of a launch and diffusion decision chain, which covers the essential decisions to be made when launching a new drug.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.013
metaresearch head score (Gemma)0.026
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.013
Threshold uncertainty score0.067

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0130.026
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.002
Science and technology studies0.0010.002
Scholarly communication0.0070.006
Open science0.0010.002
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0060.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.296
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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