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Individualised, perioperative open-lung ventilation strategy during one-lung ventilation (iPROVE-OLV): a multicentre, randomised, controlled clinical trial
Carlos Ferrando, Albert Carramiñana, Patricia Piñeiro, Lucia Mirabella, Savino Spadaro, Julián Librero, F. Ramasco, Gaetano Scaramuzzo, Oriol Cervantes, Ignacio Garutti, Ana Parera, Marta Argilaga, Gracia Herranz, Carmen Unzueta, Marc Vives, Kevin Regi, Marta Costa-Reverte, María Sonsoles Leal, Jesús Nieves‐Alonso, Esther García, Aurelio Rodríguez, Roberto Fariña, Sergio Cabrera, Elisabeth Guerra, Lucía Gallego, Alba Herrero-Izquierdo, J Vallés-Torres, Silvia Ramos, Daniel López-Herrera, Manuel de la Matta, Sertcakacilar Gokhan, Evrim Kücür, Ana Mugarra, Marina Soro, Laura García, José A. Sastre, Pilar Aguirre, Claudia Jimena Salazar, María Carolina Ramos, Diego Rolando Morocho, Ramón Trespalacios, Félix Ezequiel-Fernández, Angella Lamanna, Leonarda Pia Cantatore, Donato Laforgia, Soledad Bellas, Carlos López, Ricard Navarro‐Ripoll, Samira Martínez, Jordi Vallverdú, Adriana Jacas, María José Yepes-Temiño, F. J. Belda, Gerardo Tusman, Fernando Suárez-Sipmann, Jesús Villar, Claudia Jimena-Salazar, Féliz Ezequiel-Fernández, Donato Laforogia, Selene Martínez, Gonzalo Azparren, M. Bausili, Silvia Torres, Maria Alba Diaz, Ana Ricart, Iñaki Gascó, Fina Parramon, Maite Sanz-Iturbe, Sara García-Ballester, Esther Méndez-Arias, Rafael Cabadas, Laura M. Grosso, Ángel Ignacio Lledó Becerra, Zoraya Hussein, T.A. Sanjuan-Villarreal, María Puértolas, Blanca Izquierdo-Villarroya, Rosa Almajano, Blanca Romero, Lorena Colomina, Natividad Quesada, José Antonio Latorre, J.A. Franco, Anaïs Laval, Javier García‐Tirado, Cristina Bueno, Paula Jarén, Raquel Martínez-Serrano, Beatriz García-Latasa, Sonia Baquedano, Begoña Motilva, Belén Hernando, Miriam Herrero, Pablo Oliver-Forniés, José Luis Recuero Díaz, Fernando Carbó-Espinosa, Alejandro Lucas, Nadia Muñoz-González, Noelia Lafuente, Jesús Acosta-Martínez, Riccardo Ragazzi, Carlo Alberto Volta, Pio Maniscalco, María Pilar Arribas, María Isabel de Celis, M J Espinosa Pascual, Pedro Raúl Montoro Martínez, Olga Martínez, José Ramón Repáraz, David Domínguez, M. Alonso Fernández, Víctor Manuel Muñoz Sánchez, Blanca Pérez-Lozana, Eliseba Martín, David Fernández, Adrian González, Jandro Pico, Dalia Ahmed El-Hefny, Laura Armengol, Óscar Comino, Irene Rovira, M.J. Arguís, P. Matute, María José Carretero, Cristina Ibáñez, Juan Perdomo, Cristina Ballesteros Ruiz, Nel González, Miren González, Ana García Bolado, Sonia Trabanco, A. Largo, Alejandro Maestro, Adriana Ixquic Reyes, María José Luesma Bartolomé, Mónica Mercedes Williams, Pablo del Olmo, Bonifacio Cimadevilla, Sara Abigail Batista Pardo, Laura Huici Sancho, Laura Lascorz, J Carbonell, Raluca Florea, Sara Martínez‐Castro, Berta Monleón, Ana Rosa Jurado, Elizabeth Bárcena, Nasara Segura, Javier Cuervo, Pablo Pardo, E Ramírez Utrera, Ferran Serralta, María José Parra, Blanca Arocas, Andrea Gutiérrez, Patricia Cruz-Pardos, Francisco de la Gala-García, Guillermo Sánchez-Pedrosa, Patricia Duque-González, E. de la Fuente-Tornero, A. Puig-Ramos, Santiago García Hernández, David Martínez-Gascueña, Carlos Alberto Calvo-García, Almudena Reyes-Fierro, Emma Novoa-Lago, Rafael Anaya-Camacho, Cristina Monteserín-Matesanz, Nuria Martínez-Merino, Ana Arnalich-Montiel, Ana Gloria Pizarro-Calderón, Adela Ruiz-Ortega, Pilar Benito-Saz, Adoración Elvira Rodríguez, Beatriz García-Bünger, Sergio García-Ramos, Elena López-Gil, Mercedes Power-Esteban, Rafael Ramos-Fernándes, Raúl Sevilla-Bayón, Isabel Solchaga-Sánchez, Livio Tullo, Guido Gambetti, Antonio Carrideo, Alessandra Morelli, D Aiello, Stefania Spiga
Bibliographic record
VenueThe Lancet Respiratory Medicine · 2023
Typearticle
Languageen
FieldMedicine
TopicRespiratory Support and Mechanisms
Canadian institutionsSt. Michael's Hospital
FundersFundación Canaria Instituto de Investigación Sanitaria de CanariasEuropean Regional Development FundInstituto de Salud Carlos III
KeywordsMedicinePerioperativeVentilation (architecture)LungRandomized controlled trialIntensive care medicineClinical trialLung ventilationAnesthesiaSurgeryInternal medicine
Abstract
No abstract in any covered source. Its absence is recorded, not treated as a negative.
No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.020
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.004 |
| Meta-epidemiology (narrow) | 0.003 | 0.001 |
| Meta-epidemiology (broad) | 0.006 | 0.004 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.002 |
| Scholarly communication | 0.002 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.003 | 0.005 |
| Insufficient payload (model declined to judge) | 0.006 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
Opus teacher head0.210
GPT teacher head0.442
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".
Quick stats
Citations72
Published2023
Admission routes1
Has abstractno