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A genomic mutational constraint map using variation in 76,156 human genomes

2023· article· en· 1,330 citations· W4389367121 on OpenAlex· 10.1038/s41586-023-06045-0

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature
Topic
Genomic variations and chromosomal abnormalities
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Université de MontréalMontreal Heart InstituteUniversity of OttawaMcGill University
Funders
Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institute of Diabetes and Digestive and Kidney DiseasesNational Human Genome Research InstituteNational Institute of Mental HealthNational Institutes of HealthWellcome Trust
Keywords
Variation (astronomy)GenomeConstraint (computer-aided design)Human genomeBiologyComputational biologyGeneticsGenomicsEvolutionary biologyHuman genetic variationStructural variationGeneMathematicsPhysics
Has abstract in OpenAlex
no