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Record W4389375913 · doi:10.1177/19427786231215673

CRISPR futures: Rethinking the politics of genome editing

2023· article· en· W4389375913 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueHuman Geography · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCRISPR and Genetic Engineering
Canadian institutionsnot available
FundersFundação para a Ciência e a Tecnologia
KeywordsCommercializationPoliticsIndigenousPolitical scienceEconomic growthBiologyEconomicsEcologyLaw

Abstract

fetched live from OpenAlex

New genome editing techniques such as CRISPR-Cas9 aspire to automate and standardize laboratory practices of genetic engineering at the molecular scale. They have been promoted as a ‘revolutionary’ means of production, which will revitalize industry, transform agribusiness and adapt it to changing climatic conditions. To realize this vision, a fundamental regulatory shift is now being enacted by multiple national governments around the world from Argentina to Canada, Brazil, Australia, South Africa, the United States, the United Kingdom, Japan, China and the European Union. As corporate science is directly in the service of private entities guided by a strict market rationality, while public research is increasingly pushed to prioritize immediate ‘industrial applications’ and the achievement of measurable ‘socio-economic impact’, genomic interventions are mostly geared towards expanding , accelerating and securing the accumulation of capital on a global scale. Structural market demands are embodied in gene-edited bodies produced for commercialization. While the emerging international regulatory regime for gene-edited organisms has been largely shaped by discussions focused on technical questions of health and safety, this tendency indicates the necessity of a wider democratic debate that would include the socio-economic, ethical and ecological concerns recently stressed by indigenous and peasant movements around the world. How will these new GM bodies transform the way people live and work in agricultural lands, industrial facilities, barnyards and slaughterhouses, in biotech labs and medical clinics? How will they affect lived ecologies? What types of multi-species worlds are being constructed through bioengineering practices, by whom and according to what political visions?

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.624
Threshold uncertainty score0.350

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.291
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it