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Record W4389449640 · doi:10.1007/978-3-031-09034-9_41

New Metrics for Classifying Phylogenetic Trees Using K-means and the Symmetric Difference Metric

2023· book-chapter· en· W4389449640 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueStudies in classification, data analysis, and knowledge organization · 2023
Typebook-chapter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Phylogenetic Studies
Canadian institutionsUniversité de Sherbrooke
FundersCompute CanadaUniversité de Sherbrooke
KeywordsCluster analysisMathematicsMetric (unit)SilhouettePhylogenetic treePartition (number theory)Metric spaceTree (set theory)EmbeddingEuclidean distanceArtificial intelligenceCombinatoricsPattern recognition (psychology)Computer scienceDiscrete mathematicsBiology

Abstract

fetched live from OpenAlex

Abstract The k -means method can be adapted to any type of metric space and is sometimes linked to the median procedures. This is the case for symmetric difference metric (or Robinson and Foulds) distance in phylogeny, where it can lead to median trees as well as to Euclidean Embedding. We show how a specific version of the popular k -means clustering algorithm, based on interesting properties of the Robinson and Foulds topological distance, can be used to partition a given set of trees into one (when the data is homogeneous) or several (when the data is heterogeneous) cluster(s) of trees. We have adapted the popular cluster validity indices of Silhouette, and Gap to tree clustering with k -means. In this article, we will show results of this new approach on a real dataset (aminoacyl-tRNA synthetases). The new version of phylogenetic tree clustering makes the new method well suited for the analysis of large genomic datasets.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.533
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.132
GPT teacher head0.341
Teacher spread0.209 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it