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A High-Resolution Semi-Monolithic Slab Detector tailored for Pre-Clinical PET

2023· article· en· W4389666722 on OpenAlexaff
Yannick Kuhl, Florian Mueller, Stephan Naunheim, M. Bovelett, Janko Lambertus, David Schug, Bjoern Weissler, E. Gegenmantel, Pierre Gebhardt, Volkmar Schulz

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicMedical Imaging Techniques and Applications
Canadian institutionsHyperion Technologies (Canada)
Fundersnot available
KeywordsLyso-DetectorOpticsImage resolutionPlanarSlabMaterials scienceSilicon photomultiplierFull width at half maximumResolution (logic)Energy (signal processing)OptoelectronicsPhysicsScintillatorComputer science

Abstract

fetched live from OpenAlex

Current pre-clinical positron emission tomography (PET) scanners are often based on monolithic detectors due to their high spatial resolution and intrinsic depth-of-interaction (DOI) capabilities to reduce parallax positioning errors. However, the broad light distributions of monolithic designs can lead to drawbacks in the sensor readout and in the processing chain, e.g., dead time as well as pile up. Semi-monolithic slab detectors represent an attractive alternative as they provide a higher optical photon density while allowing a DOI determination. The cost can be assumed competitive with monoliths. This work presents a semi-monolithic detector comprising 1 mm thin high-resolution LYSO slabs coupled to a 12 × 12 channel digital SiPM tile. Currently, a detector spatial resolution (SR) (FWHM of the PSF) of 1.2 / 2.3 mm and a mean absolute error (MAE) of 0.9 / 1.1 mm is achieved in planar-monolithic / DOI direction with a correct slab identification in the planar-segmented direction of 92 % considering a [435 - 585] keV energy window. An energy resolution of 15.2 % and 461 ps coincidence timing resolution (CTR) were obtained.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.059
GPT teacher head0.400
Teacher spread0.342 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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