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Record W4389668278 · doi:10.21203/rs.3.rs-3701534/v1

Comparing Bayesian models for genetic evaluation of oocytes and embryo counts in Dairy Gir cattle

2023· preprint· en· W4389668278 on OpenAlexaff
Giovani Luis Feltes, Gabriel Soares Campos, Fernanda Santos Silva Raidan, Luiz Fernando Rodrigues Féres, Virgínia Mara Pereira Ribeiro, Jaime Araújo Cobuci

Bibliographic record

VenueResearch Square · 2023
Typepreprint
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and phenotypic traits in livestock
Canadian institutionsHendrix Genetics (Canada)
FundersConselho Nacional de Desenvolvimento Científico e TecnológicoCoordenação de Aperfeiçoamento de Pessoal de Nível Superior
KeywordsBayesian probabilityBiologyEmbryoStatisticsMathematicsGenetics

Abstract

fetched live from OpenAlex

Abstract Count traits are usually explored in livestock breeding programs and it usually does not fit into Normal distribution, requiring alternatives to adjust the phenotype to estimate accurate genetic parameters and breeding values. Alternatively, distribution such as Poisson can be used to evaluate count traits. This study aimed to compare and discuss the genetic evaluation for oocyte and embryo counts considering Gaussian (untransformed variable – LIN, transformed by logarithm – LOG, transformed by Anscombe – ANS) and Poisson (POI) distributions. The data comprised 11343 total oocytes, viable oocytes, cleaved embryos, viable embryos records of ovum pick-up from 1740 dairy Gir heifers and cows. The genetic parameters and breeding values were estimated by the MCMCglmm package of the R software. The posterior means of heritability varied from 0.40 (LIN) to 0.49 (POI) for TO; 0.39 (LIN) to 0.49 (POI) for VO; 0.30 (LOG) to 0.41 (POI) for CE; 0.19 (LIN) to 0.32 (POI) for VE, respectively. The posterior means of repeatability varied from 0.56 (LIN) to 0.65 (POI) for TO; 0.53 (LOG) to 0.63 (POI) for VO; 0.44 (LOG) to 0.60 (POI) for CE; 0.36 (LOG) to 0.56 (POI) for VE, respectively. Deviance information criterion and mean squared residuals indicated that POI model should be used for genetic evaluation of embryo and oocytes count traits. The Spearman rank correlation between estimated breeding value (EBV) for embryo and oocytes count traits computed by POI, LOG, and ANS models was high (ranging from 0.77 to 0.99), indicating little reordering among the best animals. The POI model is the most adequate for genetic evaluation, resulting in more reliable EBV for Dairy Gir cattle of oocyte and embryo counts traits.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.028
metaresearch head score (Gemma)0.047
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.028
Threshold uncertainty score0.147

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0280.047
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0020.002
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0020.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.154
GPT teacher head0.405
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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