WITHDRAWN: Digital microfluidics as an emerging tool for bacterial protocols
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Post-publication record
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Machine scores (provisional)
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- Teacher spread
- 0.268 · how far apart the two teachers sit on this one work
- Validation status
score_only:v0-immature-baseline· verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it
Abstract
Three dimensional models of cell culture enables researchers to recreate aspects of tumour biology not replicated by traditional two dimensional techniques. Here we describe a protocol to enable automated high throughput phenotypic profiling across panels of patient derived glioma stem cell spheroid models. We demonstrate the use of both live/dead cell end-points and monitor the dynamic changes in the cell cycle using cell lines expressing the FUCCI cell cycle reporter. Together, these assays provide additional insight into the mechanism of action of compound treatments over traditional cell viability assay endpoints.
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The record
- Venue
- SLAS DISCOVERY
- Topic
- Electrowetting and Microfluidic Technologies
- Field
- Engineering
- Canadian institutions
- University of Toronto
- Funders
- Cancer Research UKBrain Tumour CharitySociety for Laboratory Automation and Screening
- Keywords
- Digital microfluidicsMicrofluidicsComputer scienceNanotechnologyEngineeringMaterials scienceElectrical engineering
- Has abstract in OpenAlex
- yes