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Research on the neural circuits and treatment of anxiety

2023· article· en· W4390031410 on OpenAlexaff
Yunshu Cai

Bibliographic record

VenueTheoretical and Natural Science · 2023
Typearticle
Languageen
FieldNeuroscience
TopicMemory and Neural Mechanisms
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsAnxietyAmygdalaAnterior cingulate cortexPsychological interventionNeurosciencePsychologyPrefrontal cortexStria terminalisBiological neural networkModalitiesClinical psychologyPsychiatryMedicineCognition

Abstract

fetched live from OpenAlex

Anxiety disorders are widely recognized as one of the most widespread mental health conditions worldwide, which can have detrimental impacts on individuals, their families, and the broader communities they belong to. A clearer knowledge of the brain neural circuits linked to anxiety will be beneficial for early detection of at-risk individuals and the ability to take preventative interventions. Today, more specialized and individualized therapies for anxiety disorders have been developed as a result of neuroscientific research. The neural circuitry involves key brain regions like the amygdala, prefrontal cortex (PFC), anterior cingulate cortex (ACC), bed nucleus of the stria terminalis (BNST), and hippocampus, unraveling complex interactions contributing to anxiety pathogenesis. Treatment modalities are categorized as medicine and non-medicine approaches. This paper emphasizes the necessity for ongoing research to optimize therapeutic approaches and advocates combining pharmacological and non-medicine interventions for comprehensive anxiety disorder management, ultimately improving the well-being of affected individuals worldwide.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.004
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.134
GPT teacher head0.385
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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