Supernumerary Mediastinal Parathyroid Carcinoma Resulting in Recurrent Primary Hyperparathyroidism and Hypercalcemic Crisis: A Case Report
Bibliographic record
Abstract
Primary hyperparathyroidism is a common cause of hypercalcemia but is rarely caused by a parathyroid carcinoma.Supernumerary glands are also uncommon in the setting of recurrent disease.We present a case of an 87-year-old female who presented in a hypercalcemic crisis due to recurrent primary hyperparathyroidism.Imaging studies showed a large parathyroid adenoma in the superior mediastinum believed to be a supernumerary gland.She was taken for a joint operation with ear, nose and throat and thoracic surgery where she underwent a thoracoscopic resection of the gland.The lesion appeared to be locally invasive involving the mediastinal fat and azygous vein.Intraoperative parathyroid hormone (PTH) levels showed an appropriate drop and post-operative calcium levels normalised.Final pathology showed a 5 cm parathyroid adenoma which in the setting of her significantly elevated PTH and locally aggressive lesion would be consistent with a supernumerary parathyroid carcinoma.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.003 | 0.002 |
| Meta-epidemiology (broad) | 0.002 | 0.002 |
| Bibliometrics | 0.004 | 0.002 |
| Science and technology studies | 0.004 | 0.002 |
| Scholarly communication | 0.003 | 0.003 |
| Open science | 0.002 | 0.003 |
| Research integrity | 0.008 | 0.005 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".