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Record W4391134347 · doi:10.23880/jonam-16000379

Gold Bhasma and Silver Parpam Used in Indian Traditional Medicines. Scientific Validation of their Interaction with Human Cells

2023· article· en· W4391134347 on OpenAlexaff
Simona Bǎdilescu

Bibliographic record

VenueJournal of Natural & Ayurvedic Medicine · 2023
Typearticle
Languageen
FieldComputer Science
TopicComputational Drug Discovery Methods
Canadian institutionsConcordia University
Fundersnot available
KeywordsTraditional medicineMedicinePharmacology

Abstract

fetched live from OpenAlex

Bhasmas in Ayurveda and parpams in Siddha medicine are unique herbo-metallic/mineral preparations, effective remedies, fabricated from highly purified metals, treated with a variety of herbal decoctions and incinerated at high temperatures to, finally, obtain a metal ash, having a significantly reduced size and free of toxic effects. The processing techniques of bhasmas and their use as medicines have been described in ancient texts of Ayurveda such as Rasa Shastra, Charaka Samitha and Sushruta Sambita. It has been emphasized that, while Siddha medicine is close to Ayurveda, Siddha has been closely linked to the Tantric religious movement, traced back to the 6th century AD and it is believed that Alchemy played a more central role in Siddha medicine than in Ayurveda. Some of the most important bhasmas and parpams are briefly described; their fabrication and properties are mentioned. The study of the interaction of gold bhasma and silver parpam with human cells investigated by our group is described in the second part of this work. In this section, the cellular uptake and localization of the gold and silver particles in cancerous and normal cells have been elucidated by using, principally, the hyperspectral imaging method that combines the image with the spectral information.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.059
GPT teacher head0.326
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes1
Has abstractyes

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