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Record W4391319955 · doi:10.1101/2024.01.26.24301849

The Accuracy of Cardiac Surface Conduction Velocity Measurements

2024· preprint· en· W4391319955 on OpenAlexaff
Edward J. Vigmond, Caroline H. Roney, Jason D. Bayer, Kumaraswamy Nanthakumar

Bibliographic record

VenuemedRxiv · 2024
Typepreprint
Languageen
FieldMedicine
TopicCardiac Arrhythmias and Treatments
Canadian institutionsToronto General HospitalUniversity Health Network
Fundersnot available
KeywordsSurface (topology)Nerve conduction velocityEnvironmental scienceThermal conductionCardiologyMaterials scienceInternal medicineMathematicsMedicineGeometryComposite material

Abstract

fetched live from OpenAlex

Abstract Background: Conduction velocity (CV) is a measure of the health of myocardial tissue. It can be measured by taking differences in activation times from intracardiac electrodes. Several factors introduce error into the measurement, amongst which, ignoring the three dimensional aspect is a major detriment. The purpose of this paper was to determine if, nonetheless, there was a specific region where CV could be accurately measured. Methods: Computer simulations of three dimensional ventricles with a realistic His-Purkinje system were performed. Ventricles also included a dense scar or diffuse fibrosis. Results: A finer spatial sampling produced better agreement with true CV. Using a error limit of 10 cm/s as a threshold, measurements taken within a region less than 2 cm from the pacing site proved to be accurate. Error increased abruptly beyond this distance. The Purkinje system and tissue fibre orientation played equally major roles in leading to a surface CV which was not reflective of the CV propagation through the tissue. Conclusions: Surface CV measurements close to the pacing site taken with an electrode spacing of at most 1 mm, give reasonable estimates of tissue CV.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.015
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.015
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.059
GPT teacher head0.325
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2024
Admission routes1
Has abstractyes

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