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Planning and execution of dossier compilation of countries Germany, Canada and Australia

2023· article· en· W4391331128 on OpenAlexaboutno aff
Keloth Mounika, Y. Sirisha, K. Nagasree

Bibliographic record

VenueInternational Journal of Allied Medical Sciences and Clinical Research · 2023
Typearticle
Languageen
FieldEconomics, Econometrics and Finance
TopicPharmaceutical Economics and Policy
Canadian institutionsnot available
Fundersnot available
KeywordsPolitical scienceLibrary scienceComputer science

Abstract

fetched live from OpenAlex

To prepare and compile the Dossier required for Registration of Pharmaceutical Products as per the requirements of each countries which shall be acceptable internationally to develop one regulatory approach. To avoid variation in the documents submitted in the form of dossier for registration of Pharmaceutical Products in the different countries of the world it’s important to know the requirements of Regulatory Authorities of each countries in which the Dossier is filled for the smooth Registration. When submitting your drug benefit assessments to the German Authority or other (foreign) regulatory agencies, you need to provide your reports in a specific format. . Drug regulatory affairs in pharma industries have mandated two types of dossier namely CTD (Common Technical Dossier) and ACTD (Asean Common Technical Dossier). Regulated pharma markets (eg.USA, Europe) markets require submission of dossier in CTD format which has to provide clinical trial and bioequivalence studies. As against this, semi-regulated pharma markets (South East Asian) require ACTD format which does not require exhaustive details like CTD. For industries, it has eliminated the need to reformat the information for submission to the different ICH regulatory authorities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.022
metaresearch head score (Gemma)0.035
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.872
Threshold uncertainty score0.255

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0220.035
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0100.004
Science and technology studies0.0040.001
Scholarly communication0.0050.003
Open science0.0010.002
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0480.019

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.445
GPT teacher head0.547
Teacher spread0.103 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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Same venueInternational Journal of Allied Medical Sciences and Clinical ResearchSame topicPharmaceutical Economics and PolicyFrench-language works237,207