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Record W4391331938 · doi:10.5114/fpn.2023.131702

Lithium in mood disorders – an update

2023· article· en· W4391331938 on OpenAlexaboutno aff
Janusz Rybakowski

Bibliographic record

VenuePharmacotherapy in Psychiatry and Neurology · 2023
Typearticle
Languageen
FieldMedicine
TopicBipolar Disorder and Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsMood disordersLithium (medication)MoodPsychologyMedicineComputer sciencePsychiatryAnxiety

Abstract

fetched live from OpenAlex

in pregnancy and the postpartum period, the prevalence of lithium use and attitudes of psychiatrists towards it, and the incentives for broader lithium administration. Conclusions.The studies published between 2019 and 2023 confirmed the significant role of lithium in preventing the recurrences of mood disorders and as a therapeutic drug in acute episodes of the illness.The potentiation of antidepressants in treatment-resistant depression may constitute the second indication for lithium administration after the prevention of bipolar disorder.The optimal lithium concentration for prophylactic purposes is 0.6-0.8mmol/l.The most important among the advant ages of long-term use of the drug are suicide prevention and a possible anti-dementia effect, but also a favourable effect on the functioning of many body systems.Adverse side effects of long-term lithium administration, including its influence on kidneys, can be minimised by appropriate application and drug monitoring.The use of lithium in pregnancy and the postpartum period seems relatively safe and therapeutically efficient.Despite the many advantages of the use of lithium in affective disorders, lithium is still underutilised, so that the therapeutic potential of the drug is not fully exploited. STRESZCZENIECel. Celem pracy jest przedstawienie najważniejszych prac klinicznych, opublikowanych w latach 2019-2023, dotyczących stosowania litu w chorobach afektywnych.Przegląd piśmiennictwa.Dokonano wyboru i omówienia piśmiennictwa, które dotyczyło takich zagadnień, jak skuteczność profilaktycznego i leczniczego działania AbSTRACTObjectives.The paper aims to present the most important clinical research on lithium in mood disorders, published between 2019 and 2023.Literature review.The bibliography was selected and discussed across such topics as prophylactic and therapeutic lithium efficacy in mood disorders, therapeutic lithium concentrations and preparations, advantages and adverse side effects of long-term lithium administration, clinical factors connected with the efficacy of long-term lithium administration, the use of lithium Review article / Artykuł przeglądowy Lithium in mood disorders -an updateLit w chorobach afektywnych -aktualizacja

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.011
Threshold uncertainty score0.036

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0040.003
Science and technology studies0.0010.001
Scholarly communication0.0020.003
Open science0.0020.002
Research integrity0.0030.004
Insufficient payload (model declined to judge)0.0110.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.322
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes1
Has abstractyes

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