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Record W4391349857 · doi:10.18280/mmep.110104

Mathematical Modeling and Sensitivity Analysis of COVID-19 and Tuberculosis Coinfection with Vaccination

2024· article· en· W4391349857 on OpenAlexvenueno aff
Jonner Nainggolan, Moch. Fandi Ansori

Bibliographic record

VenueMathematical Modelling and Engineering Problems · 2024
Typearticle
Languageen
FieldMedicine
TopicSARS-CoV-2 and COVID-19 Research
Canadian institutionsnot available
Fundersnot available
KeywordsCoinfectionVaccinationTuberculosisCoronavirus disease 2019 (COVID-19)Sensitivity (control systems)VirologyMedicine2019-20 coronavirus outbreakTuberculosis vaccinesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Mycobacterium tuberculosisHuman immunodeficiency virus (HIV)OutbreakPathologyInfectious disease (medical specialty)Disease

Abstract

fetched live from OpenAlex

This research combines the COVID-19 and BCG vaccination subpopulations to examine the spread of COVID-19 coinfection and tuberculosis (TB) using a compartmental mathematical model.The model analysis yields the non-endemic and endemic equilibrium points in addition to the basic reproduction number.The vaccination variable in the model can reduce the incidence of COVID-19, TB, and coinfection.A sensitivity analysis using elasticity index is conducted and the result is that the natural death rate parameter is the most influential in relation to the accelerated spread of COVID-19 co-infection with tuberculosis.Additionally, we conduct a timedependent sensitivity analysis to determine how varying parameter values influence each subpopulation.By using this technique, we calculate the sensitivity index after reaching equilibrium of several groups of parameters, and the result is that resusceptible, immunity rate, symptomatic transition rate of TB, COVID-19 recovery rate, and natural death rate are the most influential for each group of parameters on the dynamics of each subpopulation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.009
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.023

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.009
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.296
Teacher spread0.260 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2024
Admission routes1
Has abstractyes

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