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Record W4391375563 · doi:10.7554/elife.79714

Stable population structure in Europe since the Iron Age, despite high mobility

2023· article· en· W4391375563 on OpenAlexaff
Margaret L. Antonio, Clemens L. Weiß, Ziyue Gao, Susanna Sawyer, Victoria Oberreiter, Hannah M. Moots, Jeffrey P. Spence, Olivia Cheronet, Brina Zagorc, Elisa Praxmarer, Kadir Toykan Özdoğan, Lea Demetz, Pere Gelabert, Daniel Fernandes, Michaela Lucci, Timka Alihodžić, Selma Amrani, Pavel Avetisyan, Christèle Baillif-Ducros, Željka Bedić, Audrey Bertrand, Maja Bilić, Luca Bondioli, Paulina Borówka, Emmanuel Botte, Josip Burmaz, Domagoj Bužanić, Francesca Candilio, Mirna Cvetko, Daniela De Angelis, Ivan Drnić, Kristián Elschek, Mounir Fantar, Andrej Gaspari, Gabriella Gasperetti, Francesco Genchi, Snežana Golubović, Zuzana Hukeľová, Rimantas Jankauskas, Kristina Jelinčić Vučković, Gordana Jeremić, Iva Kaić, Kevin Kazek, Hamazasp Khachatryan, Anahit Yu. Khudaverdyan, Sylvia Kirchengast, Miomir Korać, Valérie Kozlowski, Maria Krošláková, Dora Kušan Špalj, Francesco La Pastina, Marie Laguardia, Sandra Legrand, Tino Leleković, Tamara Leskovar, Wiesław Lorkiewicz, Dženi Los, Ana María Silva, René Masaryk, Vinka Matijević, Yahia Mehdi Seddik Cherifi, Nicolás Meyer, Ilija Mikić, Nataša Miladinović-Radmilović, Branka Milošević Zakić, Lina Nacouzi, Magdalena Natuniewicz-Sekuła, Alessia Nava, Christine Neugebauer-Maresch, Jan Nováček, Anna J. Osterholtz, Julianne Paige, Lujana Paraman, Dominique Piéri, Karol Pieta, Stefan Pop-Lazić, Matej Ruttkay, Mirjana Sanader, Arkadiusz Sołtysiak, Alessandra Sperduti, Tijana Stankovic Pesterac, Maria Teschler‐Nicola, Iwona Teul, Domagoj Tončinić, Julien Trapp, Dragana Vulović, Tomasz Waliszewski, Diethard Walter, Miloš Živanović, Mohamed el Mostefa Filah, Morana Čaušević-Bully, Mario Šlaus, Dušan Borić, Mario Novak, Alfredo Coppa, Ron Pinhasi, Jonathan K. Pritchard

Bibliographic record

VenueeLife · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicForensic and Genetic Research
Canadian institutionsMusée de la Civilisation
FundersAustrian Science FundNational Human Genome Research InstituteHoward Hughes Medical InstituteNational Institutes of HealthNational Science Foundation
KeywordsBiological dispersalPopulationDemographic historyGeographyPrehistoryAncient DNAPeriod (music)Human migrationEconomic geographyPanmixiaGenetic structureDemographyEvolutionary biologyBiologyArchaeologyGenetic variation

Abstract

fetched live from OpenAlex

Ancient DNA research in the past decade has revealed that European population structure changed dramatically in the prehistoric period (14,000-3000 years before present, YBP), reflecting the widespread introduction of Neolithic farmer and Bronze Age Steppe ancestries. However, little is known about how population structure changed from the historical period onward (3000 YBP - present). To address this, we collected whole genomes from 204 individuals from Europe and the Mediterranean, many of which are the first historical period genomes from their region (e.g. Armenia and France). We found that most regions show remarkable inter-individual heterogeneity. At least 7% of historical individuals carry ancestry uncommon in the region where they were sampled, some indicating cross-Mediterranean contacts. Despite this high level of mobility, overall population structure across western Eurasia is relatively stable through the historical period up to the present, mirroring geography. We show that, under standard population genetics models with local panmixia, the observed level of dispersal would lead to a collapse of population structure. Persistent population structure thus suggests a lower effective migration rate than indicated by the observed dispersal. We hypothesize that this phenomenon can be explained by extensive transient dispersal arising from drastically improved transportation networks and the Roman Empire's mobilization of people for trade, labor, and military. This work highlights the utility of ancient DNA in elucidating finer scale human population dynamics in recent history.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.283
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations77
Published2023
Admission routes1
Has abstractyes

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