MétaCan
Menu
Back to cohort
Record W4391422492 · doi:10.1371/journal.ppat.1011930

It’s uncomplicated: Prevention of urinary tract infections in an era of increasing antibiotic resistance

2024· article· en· W4391422492 on OpenAlexafffund
Lori L. Burrows

Bibliographic record

VenuePLoS Pathogens · 2024
Typearticle
Languageen
FieldMedicine
TopicUrinary Tract Infections Management
Canadian institutionsMcMaster University
FundersCanada Research Chairs
KeywordsUrinary systemAntibiotic resistanceAntibioticsMedicineIntensive care medicineMicrobiologyInternal medicineBiology

Abstract

fetched live from OpenAlex

Urinary tract infections (UTIs) rank near the top of the long list of medical issues that can affect humans. They are the most common reason for outpatient visits in the United States (US), and clinics around the world see millions of cases annually. UTIs can be broadly categorized as uncomplicated infections that are usually straightforward to resolve, versus complicated UTIs that because of the pathogen, anatomy or health status of the patient, and/or presence of medical devices such as urinary catheters or stents, are more challenging to resolve. Complicated UTIs are associated with formation of antibiotic-tolerant bacterial or fungal biofilm communities on medical devices during prolonged use, and risk is correlated with duration of device placement Although uncomplicated UTIs are relatively simple to treat, they can be recurrent, defined as 2 or more symptomatic infections in 6 months, or 3 in 12 months, often with the same pathogen If inadequately treated, both types of UTIs can progress to severe disease, including kidney damage and sepsis, with the urinary tract being a major source of bloodstream infections

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.436
Threshold uncertainty score0.530

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.313
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2024
Admission routes2
Has abstractyes

Explore more

Same venuePLoS PathogensSame topicUrinary Tract Infections ManagementFrench-language works237,207