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Record W4391515339 · doi:10.1016/j.cstres.2024.01.003

Second international symposium on the chaperone code, 2023

2024· article· en· W4391515339 on OpenAlexaff
Johannes Büchner, Milad J. Alasady, Sarah J. Backe, Brian S. J. Blagg, Richard L. Carpenter, Giorgio Colombo, Ioannis Gelis, D.T. Gewirth, Lila M. Gierasch, Walid A. Houry, Jill L. Johnson, Byoung Heon Kang, Aimee W. Kao, Paul LaPointe, Seema Mattoo, Amie J. McClellan, Leonard Μ. Neckers, Chrisostomos Prodromou, Andrea Rasola, Rebecca Sager, Maria A. Theodoraki, Andrew W. Truman, Matthias C. Truttman, Natasha E. Zachara, Dimitra Bourboulia, Mehdi Mollapour, Mark R. Woodford

Bibliographic record

VenueCell Stress and Chaperones · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicHeat shock proteins research
Canadian institutionsUniversity of AlbertaUniversity of Toronto
FundersNational Institute of General Medical SciencesState University of New York Upstate Medical UniversityNational Institute of Neurological Disorders and StrokeState University of New York
KeywordsChaperone (clinical)Political scienceComputational biologyBiologyEngineering ethicsMedicineEngineeringPathology

Abstract

fetched live from OpenAlex

The 2nd International Symposium on the Chaperone Code took place on October 26-28, 2023 at the Hilton Alexandria Old Town, VA, USA. The event featured more than 100 attendees from ten countries and provided a dynamic platform for established researchers, emerging investigators, postdoctoral fellows, and students to share insights and ideas on diverse facets of molecular chaperones with a strong focus on their regulation by post-translational modifications. The format fostered discussions and collaboration among participants. From the different contributions, future trajectories of the chaperone code field emerged, including avenues for further exploration and innovation in understanding and manipulating chaperone function in different diseases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.031
Threshold uncertainty score0.105

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0030.001
Scholarly communication0.0060.003
Open science0.0010.005
Research integrity0.0040.005
Insufficient payload (model declined to judge)0.0310.012

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.261
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2024
Admission routes1
Has abstractyes

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