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Record W4391515339 · doi:10.1016/j.cstres.2024.01.003

Second international symposium on the chaperone code, 2023

2024· article· en· W4391515339 on OpenAlexaff
Johannes Büchner, Milad J. Alasady, Sarah J. Backe, Brian S. J. Blagg, Richard L. Carpenter, Giorgio Colombo, Ioannis Gelis, D.T. Gewirth, Lila M. Gierasch, Walid A. Houry, Jill L. Johnson, Byoung Heon Kang, Aimee W. Kao, Paul LaPointe, Seema Mattoo, Amie J. McClellan, Leonard Μ. Neckers, Chrisostomos Prodromou, Andrea Rasola, Rebecca Sager, Maria A. Theodoraki, Andrew W. Truman, Matthias C. Truttman, Natasha E. Zachara, Dimitra Bourboulia, Mehdi Mollapour, Mark R. Woodford

Bibliographic record

VenueCell Stress and Chaperones · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicHeat shock proteins research
Canadian institutionsUniversity of AlbertaUniversity of Toronto
FundersNational Institute of General Medical SciencesState University of New York Upstate Medical UniversityNational Institute of Neurological Disorders and StrokeState University of New York
KeywordsChaperone (clinical)Political scienceComputational biologyBiologyEngineering ethicsMedicineEngineeringPathology

Abstract

fetched live from OpenAlex

The 2nd International Symposium on the Chaperone Code took place on October 26-28, 2023 at the Hilton Alexandria Old Town, VA, USA. The event featured more than 100 attendees from ten countries and provided a dynamic platform for established researchers, emerging investigators, postdoctoral fellows, and students to share insights and ideas on diverse facets of molecular chaperones with a strong focus on their regulation by post-translational modifications. The format fostered discussions and collaboration among participants. From the different contributions, future trajectories of the chaperone code field emerged, including avenues for further exploration and innovation in understanding and manipulating chaperone function in different diseases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.386
Threshold uncertainty score0.814

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.261
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2024
Admission routes1
Has abstractyes

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