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Record W4391541920 · doi:10.21203/rs.3.rs-3914714/v1

Unveiling Pandemic Patterns: A Detailed Analysis of Transmissibility and Severity Parameters Across Four COVID-19 Waves in Bogotá, Colombia

2024· preprint· en· W4391541920 on OpenAlexfundno aff
Zulma M. Cucunubá, David Santiago Quevedo, Nicolas Domigues, Diego de Miguel‐Pérez, Maria Alejandra Cabrera, Juan David Serrano, Felipe Segundo Abril, Diane Moyano, Diana Sofía Rios, Manuel González, Charles Whittaker

Bibliographic record

VenueResearch Square · 2024
Typepreprint
Languageen
FieldMathematics
TopicCOVID-19 epidemiological studies
Canadian institutionsnot available
FundersInternational Development Research CentreWellcome Trust
KeywordsTransmissibility (structural dynamics)Coronavirus disease 2019 (COVID-19)Pandemic2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)GeographyVirologyMedicineOutbreakPhysicsAcousticsPathology

Abstract

fetched live from OpenAlex

Abstract This retrospective study on COVID-19's four waves in Bogotá, Colombia, scrutinises 1.77 million cases from March 2020 to April 2022, revealing significant shifts in both transmissibility and severity. The study highlights dynamic changes in the instantaneous reproduction number (Rt), with the highest values (> 2.5) corresponding to the ancestral and Omicron variants. There was a notable 88% decrease in the Case Fatality Ratio (CFR) from the first to the fourth wave, emphasising changing severity levels. The third wave, marked by the Mu variant, saw the highest case and death counts, yet paradoxically showed a decrease in CFR and an increase in the hospitalisation fatality ratio. Conversely, the fourth wave, dominated by Omicron, had the lowest severity despite higher hospitalisation rates in children. Additionally, the study records a consistent reduction in average hospital and ICU stay durations, from 10.84 days to 7.85 days and from 16.2 days to 12.4 days respectively, across the waves. These findings underscore the importance of ongoing epidemiological surveillance and adaptable public health strategies in lower-middle-income regions like Bogotá, deepening our understanding of COVID-19's impact in Latin America.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.165
Threshold uncertainty score0.328

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.474
GPT teacher head0.556
Teacher spread0.082 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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