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Record W4391678546 · doi:10.21203/rs.3.rs-3800060/v1

Western Ontario and McMaster Universities Arthritis Index (WOMAC) Optimal Value in Diagnosing Overlapping Fibromyalgia: A Multivariate Study on Knee Osteoarthritis Short running head: WOMAC Value in Diagnosing Overlapping Fibromyalgia

2024· preprint· en· W4391678546 on OpenAlexaboutno aff
Abdolkarim Haji Ghadery, Kimia Jazi, Mohaddeseh Ebrahimpour Roodposhti, Roxana Safari, Amirhossein Parsaei, Behnam Amini, Maryam Masoumi, Rasoul Shajari, Mohammad Aghaali, Somaye Sadat Rezaei

Bibliographic record

VenueResearch Square · 2024
Typepreprint
Languageen
FieldMedicine
TopicFibromyalgia and Chronic Fatigue Syndrome Research
Canadian institutionsnot available
Fundersnot available
KeywordsWOMACFibromyalgiaOsteoarthritisMedicinePhysical therapyValue (mathematics)Multivariate statisticsPhysical medicine and rehabilitationMathematicsAlternative medicineStatisticsPathology

Abstract

fetched live from OpenAlex

Abstract Background: In the current study we aim to assess the prevalence of overlapping FM in a population of knee OA patients and to evaluate the diagnostic performance of WOMAC for FM in OA patients. Methods: We recruited a consecutive sample of 100 knee OA patients. They were assessed for pain, stiffness and function using WOMAC and overlapping FM using ACR 2010 criteria. To find independent predictors for fibromyalgia diagnosis, univariate and multivariate logistic regression analyses were utilized. ROC curves and Youden's J index were used to identify the best cutoff values for predictor parameters. Results: 41 in 100 OA patients also had fibromyalgia based on ACR criteria. Age, BMI and WOMAC score were significantly higher in patients with overlapping FM than patients without FM. Univariate analysis identified that the age, BMI and WOMAC score (Ps = 0.029, 0.041, and < 0.001, respectively) are significantly associated with overlapping FM diagnosis. In multivariate analysis, WOMAC score (OR: 0.93 (95% CI 0.90–0.97), P < 0.001) was identified as independent predictors of overlapping FM. Using ROC, the AUC of WOMAC score was 0.715 (95%CI: 0.614–0.817) and the optimum cutoff point for WOMAC for FM was 43.5. Conclusions: It is concluded from this study that WOMAC scores > 43.5 are useful for suggesting FM as a secondary diagnosis in knee OA patients. Future studies are necessary to establish the results of the current study in a more general context, given the limited available evidence.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.012
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.025

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.012
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.358
Teacher spread0.310 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

Explore more

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