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Record W4391850381 · doi:10.1016/j.jmig.2024.02.004

A Call for New Theories on the Pathogenesis and Pathophysiology of Endometriosis

2024· article· en· W4391850381 on OpenAlexafffund
Michel Canis, Jason Abbott, Maurício Simões Abrão, Moamar Al‐Jefout, Mohamed A. Bedaiwy, Giuseppe Benagiano, Katherine A. Burns, Francisco Carmona, Charles Chapron, Hilary Critchley, Dominique de Ziegler, Tommaso Falcone, Asgerally T. Fazleabas, Simone Ferrero, Juan A. García-Velasco, Caroline E. Gargett, Erin Greaves, Linda G. Griffith, Sun-Wei Guo, Marwan Habiba, Tasuku Harada, M. Louise Hull, Neil P. Johnson, Yuval Kaufman, Keith B Issacson, Khaleque Newaz Khan, Philippe A. Koninckx, Bruce A. Lessey, Dan C. Martin, Sachiko Matsuzaki, Gita D. Mishra, Yutaka Osuga, Felice Petraglia, A.A. Popov, Horace Roman, Andrea Romano, Philippa T. K. Saunders, Tamer Seckin, Edgardo Somigliana, Hugh S. Taylor, Robert N. Taylor, Paolo Vercellini, Paola Viganò

Bibliographic record

VenueJournal of Minimally Invasive Gynecology · 2024
Typearticle
Languageen
FieldMedicine
TopicEndometriosis Research and Treatment
Canadian institutionsUniversity of British Columbia
FundersWarwick Medical SchoolNational Health and Medical Research CouncilMedical Research CouncilDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of PittsburghUniversity of LeicesterCollege of Medicine, University of CincinnatiGedeon RichterNordic Pharma GroupCatholic University of KoreaAssistance publique-Hôpitaux de ParisCollege of Engineering, Michigan State UniversityFondazione IRCCS Ca' Granda Ospedale Maggiore PoliclinicoFaculdade de Medicina da Universidade de São PauloCentre National de la Recherche ScientifiqueUniversitat de BarcelonaUniversity of TokyoHealth Science Center, University of TennesseeDepartment of Health and Aged Care, Australian GovernmentUniversité de ParisFudan UniversityInternational Society of Ultrasound in Obstetrics and GynecologyMonash UniversityUniversity of EdinburghCleveland ClinicPfizerUniversità degli Studi di MilanoUniversità degli Studi di FirenzeAmerican Psychiatric Institute for Research and EducationVirginia Commonwealth UniversityEndometriosis Foundation of AmericaRaymond and Beverly Sackler Institute for Biological, Physical and Engineering Sciences, Yale UniversityUniversiteit MaastrichtUniversity of New South WalesYale UniversityAustralian GovernmentUniversity of CincinnatiUnited Arab Emirates UniversityFlinders UniversityNational Institute of Child Health and Human DevelopmentStem Cells AustraliaUniversity of British ColumbiaMichigan State UniversityNorthwell HealthUniversity at BuffaloEuropean CommissionMassachusetts Institute of TechnologyUniversity of WarwickCollege of Medicine, Catholic University of KoreaNational Stem Cell Foundation of AustraliaIntuitive SurgicalHudson Institute of Medical ResearchU.S. Department of Defense
KeywordsConvictionPaceMedicineEndometriosisDiseasePathogenesisBioinformaticsImmunologyPathologyLaw

Abstract

fetched live from OpenAlex

This group was formed out of the conviction that endometriosis research has not progressed at a pace in proportion to disease severity and the negative impact on women's quality of life. Furthermore, advancement in our understanding of this condition requires a quantum shift based on new theories of disease pathogenesis. With this conviction, this international group calls for new theories that may improve the understanding of this condition, leading to optimized management or even prevention. To facilitate this, a dedicated website serving as a repository where all proposed theories can be reviewed and critiqued by peers will be created.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.032
metaresearch head score (Gemma)0.029
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.032
Threshold uncertainty score0.168

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0320.029
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.003
Bibliometrics0.0050.002
Science and technology studies0.0030.017
Scholarly communication0.0110.028
Open science0.0040.008
Research integrity0.0160.043
Insufficient payload (model declined to judge)0.0170.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.305
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations36
Published2024
Admission routes2
Has abstractyes

Explore more

Same venueJournal of Minimally Invasive GynecologySame topicEndometriosis Research and TreatmentFrench-language works237,207