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Record W4391878684 · doi:10.32920/25234414.v1

The Preparation of New Polystyrenic Onium and Substituted Poly(Thionylphosphazene) Antimicrobials

2024· preprint· en· W4391878684 on OpenAlexaff
Rachele N. Carafa

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldChemistry
TopicAntimicrobial agents and applications
Canadian institutionsToronto Metropolitan University
Fundersnot available
KeywordsPolymerizationMonomerPolymerCopolymerStyrenePolymer chemistryAlkylChemistryCatalysisMaterials scienceLewis acids and basesCombinatorial chemistryOrganic chemistry

Abstract

fetched live from OpenAlex

<p>With increasing concern over AMR in bacteria, the synthesis of traditional and non-traditional antimicrobial polymers is of interest. The first project focuses on preparing new polystyrenic quaternary compounds that will be grafted to plastic surfaces. Three quaternary styrenic polymers (4-6) and their respective random copolymers with styrene (7-9) were synthesized and grafted onto HDPE, where biological testing of coatings 4, 5 and 7 using the LDI protocol showed some bacterial reduction with alkyl chain lengths ≥ 4. The second project focuses on synthesizing novel thionylphosphazene monomers and looking into greener polymerization routes. Two novel thionylphosphazene monomers (13-14) were synthesized and a greener polymerization route was obtained using Lewis acid-catalyzed microwave irradiation. The third project involves undertaking DFT calculations of various cyclic thionylphosphazenes to study alternate polymerization routes of these compounds. Energy calculations showed the potential for substituted thionylphosphazenes with small substituents to polymerize under ambient temperatures with Lewis acid catalysts.</p>

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.050
Threshold uncertainty score0.820

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.285
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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