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Record W4392018844 · doi:10.3389/fnhum.2024.1320806

Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: pushing the forefront of neuromodulation with functional network mapping, biomarkers for adaptive DBS, bioethical dilemmas, AI-guided neuromodulation, and translational advancements

2024· article· en· W4392018844 on OpenAlexaff
Kara A. Johnson, Nico U.F. Dosenbach, Evan M. Gordon, Cristin G. Welle, Kevin B. Wilkins, Helen Brontë‐Stewart, Valerie Voon, Takashi Morishita, Yuki Sakai, Amanda R. Merner, Gabriel Lázaro‐Muñoz, Theresa Williamson, Andreas Horn, Ro’ee Gilron, Jonathan O’Keeffe, Aryn H. Gittis, Wolf‐Julian Neumann, Simon Little, Nicole R. Provenza, Sameer A. Sheth, Alfonso Fasano, Abbey Holt-Becker, Robert S. Raike, Lisa Moore, Yagna Pathak, David Greene, Sara Marceglia, Lothar Krinke, Huiling Tan, Hagai Bergman, Monika Pötter‐Nerger, Bomin Sun, Laura Y. Cabrera, Cameron C. McIntyre, Noam Harel, Helen S. Mayberg, Andrew D. Krystal, Nader Pouratian, Philip A. Starr, Kelly D. Foote, Michael S. Okun, Joshua K. Wong

Bibliographic record

VenueFrontiers in Human Neuroscience · 2024
Typearticle
Languageen
FieldMedicine
TopicNeurological disorders and treatments
Canadian institutionsOntario Brain InstituteToronto Western HospitalUniversity of TorontoUniversity Health Network
FundersJanssen PharmaceuticalsNational Institute of Neurological Disorders and StrokeNational Institute of Nursing ResearchNational Institute of Mental HealthCentral Research Institute, Fukuoka UniversityJapan Society for the Promotion of ScienceNational Center for Advancing Translational SciencesMedical Research CouncilIntellectual and Developmental Disabilities Research CenterIdorsia PharmaceuticalsFukuoka UniversityParkinson AllianceBundesministerium für Bildung und ForschungJapan Agency for Medical Research and DevelopmentDeutsche ForschungsgemeinschaftUniversity of Florida FoundationAssociation France ParkinsonUniversity of FloridaEuropean CommissionWellcome TrustHope Center for Neurological DisordersVanderbilt UniversityEU Joint Programme – Neurodegenerative Disease ResearchEisaiNational Institute of Biomedical Imaging and BioengineeringIpsenJazz PharmaceuticalsBoston Scientific CorporationHarmony BiosciencesDefense Advanced Research Projects AgencyBachmann-Strauss Dystonia and Parkinson FoundationParkinson's FoundationNeurocrine BiosciencesNational Institutes of HealthHope for Depression Research FoundationSunovionAbbott Laboratories
KeywordsNeuromodulationDeep brain stimulationNeuroscienceNeuroethicsPsychologyMedicineParkinson's diseaseDiseaseStimulation

Abstract

fetched live from OpenAlex

The Deep Brain Stimulation (DBS) Think Tank XI was held on August 9-11, 2023 in Gainesville, Florida with the theme of "Pushing the Forefront of Neuromodulation". The keynote speaker was Dr. Nico Dosenbach from Washington University in St. Louis, Missouri. He presented his research recently published in Nature inn a collaboration with Dr. Evan Gordon to identify and characterize the somato-cognitive action network (SCAN), which has redefined the motor homunculus and has led to new hypotheses about the integrative networks underpinning therapeutic DBS. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers, and researchers (from industry and academia) can freely discuss current and emerging DBS technologies, as well as logistical and ethical issues facing the field. The group estimated that globally more than 263,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. This year's meeting was focused on advances in the following areas: cutting-edge translational neuromodulation, cutting-edge physiology, advances in neuromodulation from Europe and Asia, neuroethical dilemmas, artificial intelligence and computational modeling, time scales in DBS for mood disorders, and advances in future neuromodulation devices.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.185
Threshold uncertainty score0.437

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.279
Teacher spread0.246 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations30
Published2024
Admission routes1
Has abstractyes

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