Fatal Escitalopram-Induced Leukocytoclastic Vasculitis Clinically Simulating Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome: Digging Deeper into an Uncommon Presentation
Bibliographic record
Abstract
Dermatitis®Ahead of Print LettersFatal Escitalopram-Induced Leukocytoclastic Vasculitis Clinically Simulating Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome: Digging Deeper into an Uncommon PresentationBouraoui Ouni, Khadija Mansour, Maha Lahouel, Malek Sassi, Nesrine Ben-Sayed, Badreddine Sriha, Mohamed Denguezli, Neila Fathallah, and Raoudha SlimBouraoui OuniE-mail Address: [email protected]https://orcid.org/0009-0001-6380-8723Department of Pharmacology, Faculty of Medicine of Sousse, Sousse, TunisiaB.O. and K.M. wrote and revised the manuscript. M.L., M.D., and M.S. made the diagnosis, patient's supervision, and follow-up. B.S. contributed to the diagnosis through anatomopathological examination. N.B.-S., N.F., and R.S. performed literature search. All authors have read and approved the final manuscript.Search for more papers by this author, Khadija Mansourhttps://orcid.org/0000-0001-9397-1102Department of Pharmacology, Faculty of Medicine of Sousse, Sousse, TunisiaB.O. and K.M. wrote and revised the manuscript. M.L., M.D., and M.S. made the diagnosis, patient's supervision, and follow-up. B.S. contributed to the diagnosis through anatomopathological examination. N.B.-S., N.F., and R.S. performed literature search. All authors have read and approved the final manuscript.Search for more papers by this author, Maha LahouelDepartment of Dermatology, Farhat Hached Hospital, Sousse, TunisiaB.O. and K.M. wrote and revised the manuscript. M.L., M.D., and M.S. made the diagnosis, patient's supervision, and follow-up. B.S. contributed to the diagnosis through anatomopathological examination. N.B.-S., N.F., and R.S. performed literature search. All authors have read and approved the final manuscript.Search for more papers by this author, Malek SassiDepartment of Pharmacology, Faculty of Medicine of Sousse, Sousse, TunisiaB.O. and K.M. wrote and revised the manuscript. M.L., M.D., and M.S. made the diagnosis, patient's supervision, and follow-up. B.S. contributed to the diagnosis through anatomopathological examination. N.B.-S., N.F., and R.S. performed literature search. All authors have read and approved the final manuscript.Search for more papers by this author, Nesrine Ben-SayedDepartment of Clinical Hematology, Farhat Hached Hospital, Sousse, TunisiaB.O. and K.M. wrote and revised the manuscript. M.L., M.D., and M.S. made the diagnosis, patient's supervision, and follow-up. B.S. contributed to the diagnosis through anatomopathological examination. N.B.-S., N.F., and R.S. performed literature search. All authors have read and approved the final manuscript.Search for more papers by this author, Badreddine SrihaDepartment of Anatomopathology, Farhat Hached Hospital, Sousse, TunisiaB.O. and K.M. wrote and revised the manuscript. M.L., M.D., and M.S. made the diagnosis, patient's supervision, and follow-up. B.S. contributed to the diagnosis through anatomopathological examination. N.B.-S., N.F., and R.S. performed literature search. All authors have read and approved the final manuscript.Search for more papers by this author, Mohamed DenguezliDepartment of Dermatology, Farhat Hached Hospital, Sousse, TunisiaB.O. and K.M. wrote and revised the manuscript. M.L., M.D., and M.S. made the diagnosis, patient's supervision, and follow-up. B.S. contributed to the diagnosis through anatomopathological examination. N.B.-S., N.F., and R.S. performed literature search. All authors have read and approved the final manuscript.Search for more papers by this author, Neila FathallahDepartment of Pharmacology, Faculty of Medicine of Sousse, Sousse, TunisiaB.O. and K.M. wrote and revised the manuscript. M.L., M.D., and M.S. made the diagnosis, patient's supervision, and follow-up. B.S. contributed to the diagnosis through anatomopathological examination. N.B.-S., N.F., and R.S. performed literature search. All authors have read and approved the final manuscript.Search for more papers by this author, and Raoudha SlimDepartment of Pharmacology, Faculty of Medicine of Sousse, Sousse, TunisiaB.O. and K.M. wrote and revised the manuscript. M.L., M.D., and M.S. made the diagnosis, patient's supervision, and follow-up. B.S. contributed to the diagnosis through anatomopathological examination. N.B.-S., N.F., and R.S. performed literature search. All authors have read and approved the final manuscript.Search for more papers by this authorPublished Online:21 Feb 2024https://doi.org/10.1089/derm.2023.0323AboutSectionsView articleView Full TextPDF/EPUB Permissions & CitationsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookXLinked InRedditEmail View articleFiguresReferencesRelatedDetails Volume 0Issue 0 Information© 2024 American Contact Dermatitis Society. All Rights Reserved.To cite this article:Bouraoui Ouni, Khadija Mansour, Maha Lahouel, Malek Sassi, Nesrine Ben-Sayed, Badreddine Sriha, Mohamed Denguezli, Neila Fathallah, and Raoudha Slim.Fatal Escitalopram-Induced Leukocytoclastic Vasculitis Clinically Simulating Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome: Digging Deeper into an Uncommon Presentation.Dermatitis®.ahead of printhttp://doi.org/10.1089/derm.2023.0323Online Ahead of Print:February 21, 2024 TopicsEosinophilic esophagitis PDF download
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.002 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.007 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".