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Record W4392199830 · doi:10.1093/plcell/koae059

It takes two to tango: Plant hosts influence bacterial effector function through post-translational modifications

2024· editorial· en· W4392199830 on OpenAlexaff
Bradley Laflamme

Bibliographic record

VenueThe Plant Cell · 2024
Typeeditorial
Languageen
FieldAgricultural and Biological Sciences
TopicPlant-Microbe Interactions and Immunity
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsEffectorBiologyPseudomonas syringaeVirulenceSUMO proteinArabidopsisFunction (biology)Cell biologyUbiquitinSecretionMicrobiologyPathogenGeneticsGeneMutantBiochemistry

Abstract

fetched live from OpenAlex

Many bacterial phytopathogens secrete virulence proteins (often termed effectors) directly into plant cells to aid in infecting and colonizing host tissues (Cunnac et al., 2011). While certain effectors have well-established virulence functions inside of the plant cell -typically involving interference with host immune mechanisms -we have a paler understanding of how the host might influence effector activities. After all, eukaryotic cells are wired with organelles and biological processes which prokaryotes don't possess. However, prokaryotic pathogens, despite lacking these cellular mechanisms, display an intriguing ability to leverage and exploit eukaryotic features during infection. Thus, it's exciting to consider how coevolution has driven prokaryotic pathogens to integrate eukaryotic tools into their infection strategy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.376
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.233
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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