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Record W4392383041 · doi:10.1073/pnas.2320521121

Reply to Kaestner et al.: Pioneering quantitative platforms for stored red blood cell assessment open the door for precision transfusion medicine

2024· article· en· W4392383041 on OpenAlexaff
Ziya Işıksaçan, Angelo D’Alessandro, David H. McKenna, Shannon N. Tessier, Erdem Kucukal, Aslıhan Gökaltun, Nishaka William, Rebecca D. Sandlin, John C. Bischof, Narla Mohandas, Michael P. Busch, Çağlar Elbüken, Umut A. Gürkan, Mehmet Toner, Jason P. Acker, Martin L. Yarmush, O. Berk Usta

Bibliographic record

VenueProceedings of the National Academy of Sciences · 2024
Typearticle
Languageen
FieldMedicine
TopicErythrocyte Function and Pathophysiology
Canadian institutionsCanadian Blood ServicesUniversity of Alberta
FundersNational Institute of Allergy and Infectious DiseasesNational Institute of General Medical SciencesOulun YliopistoNational Heart, Lung, and Blood InstituteAcademy of FinlandNational Institutes of HealthNational Science Foundation
KeywordsVertebrateBiologyShrimpClawAnatomyEvolutionary biologyZoologyEcology

Abstract

fetched live from OpenAlex

employment, and consulting.Hemex Health Inc. offers point-of-care diagnostics for hemoglobin disorders, anemia, and malaria.BioChip Labs Inc. offers commercial clinical microfluidic biomarker assays for inherited or acquired blood disorders.Xatek Inc. offers point-of-care global assays to evaluate the hemostatic process.DxNow Inc. offers microfluidic and bio-imaging technologies for in vitro fertilization, forensics, and diagnostics.Competing interests of Case Western Reserve University employees are overseen and managed by the Conflict of Interests Committee according to a Conflict-of-Interest Management Plan.The study was conducted prior to E.K. employment at IDEXX Laboratories, and the ideas expressed are not in his capacity as an IDEXX employee.A.D. serves on the Scientific Advisory Board of Hemanext Inc. and Macopharma Inc., and his competing interests are managed by the University of Colorado in accordance with their conflict-of-interest policies.S.N.T

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.036
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.032
Threshold uncertainty score0.042

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.036
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.001
Science and technology studies0.0020.005
Scholarly communication0.0040.006
Open science0.0030.003
Research integrity0.0320.058
Insufficient payload (model declined to judge)0.0050.008

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.092
GPT teacher head0.408
Teacher spread0.316 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueProceedings of the National Academy of SciencesSame topicErythrocyte Function and PathophysiologyFrench-language works237,207