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Record W4392459173 · doi:10.1530/rep-23-0459

Naked mole rat ovaries allow investigation of ovarian reserve, <i>in vitro</i> germ cell expansion, and oocyte <i>in vitro</i> maturation within a single sample

2024· article· en· W4392459173 on OpenAlexafffund
Gretchen M Rosado, Ana Martínez-Marchal, Mariela Faykoo-Martinez, Melissa M. Holmes, Miguel A. Brieño‐Enríquez

Bibliographic record

VenueReproduction · 2024
Typearticle
Languageen
FieldMedicine
TopicReproductive Biology and Fertility
Canadian institutionsAmorfix (Canada)Hospital for Sick ChildrenUniversity of Toronto
FundersNatural Sciences and Engineering Research Council of CanadaNational Institutes of HealthEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentAndrew W. Mellon Foundation
KeywordsIn vitro maturationOocyteIn vitroOvaryAndrologyOvarian reserveGerm cellBiologyIn vitro fertilisationCell biologyOvarian tissueChemistryEmbryoMedicineEndocrinologyBiochemistryPregnancyInfertilityGenetics

Abstract

fetched live from OpenAlex

Recently, we described that in the naked mole rat ovary it is possible to study the ovarian reserve and the mitotic expansion of the germ cell postnatally. Herein, we show oocyte in vitro maturation and in vitro germ cell expansion using the same ovary.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.088
Threshold uncertainty score0.689

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.251
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes2
Has abstractyes

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