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The impact of diabetes on postoperative infections in colorectal cancer: A meta-analysis

2024· article· en· W4392470481 on OpenAlex
Xueyu Peng, Yuanyuan Ning

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueTheoretical and Natural Science · 2024
Typearticle
Languageen
FieldMedicine
TopicGastric Cancer Management and Outcomes
Canadian institutionsnot available
Fundersnot available
KeywordsFunnel plotPublication biasMedicineMeta-analysisColorectal cancerInclusion and exclusion criteriaSubgroup analysisDiabetes mellitusInternal medicineOdds ratioCancerPathologyAlternative medicine

Abstract

fetched live from OpenAlex

Objective: This study aims to analyze and summarize the evidence concerning the relationship between diabetes and postoperative infections in colon cancer through a literature review. Methods: A comprehensive search was conducted on Chinese databases, including CNKI, VIP, Wanfang, and the biomedical literature database, as well as the English database PubMed. The search covered the period from February 1, 2003, to February 28, 2023. The Newcastle-Ottawa Scale was employed to score the included literature, and funnel plots along with Egger’s regression test were used to analyze publication bias. Stata 12.0 was utilized for the analysis of the collected raw data. Results: Following inclusion and exclusion criteria, this study incorporated seven retrospective studies, with a total of 4607 cases in the infection group and 9102 cases in the non-infection group. The quality scores of the seven studies ranged between 7 and 8 points. Funnel plot and Egger’s regression test analyses revealed no significant publication bias in the included literature. A correlation was identified between diabetes and postoperative infections in colon cancer, implicating diabetes as a risk factor for such infections. Subgroup analysis indicated that nationality, surgical methods, and infection types had no significant impact on the meta-analysis results. Conclusion: The analysis revealed a significant correlation between diabetes and postoperative infections in colon cancer. Diabetes emerged as a risk factor for postoperative infections, with odds ratios (OR) of 3.82 (P>0.1) and 95% CI of 2.91-5.01. Controlling blood glucose levels was associated with a reduced risk of postoperative infections in colon cancer.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.863
Threshold uncertainty score0.429

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.002
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.335
Teacher spread0.322 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it