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Record W4392473478 · doi:10.1242/jcs.261987

Perspectives on polarity – exploring biological asymmetry across scales

2024· article· en· W4392473478 on OpenAlexafffund
Marieke M. Glazenburg, Nynke Marije Hettema, Liedewij Laan, Ophélie Remy, Géraldine Laloux, Thibaut Brunet, Xin Chen, Yee Han Tee, Wenyu Wen, Mohd Suhail Rizvi, Mohit Kumar Jolly, Meghan Riddell

Bibliographic record

VenueJournal of Cell Science · 2024
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicProtist diversity and phylogeny
Canadian institutionsUniversity of Alberta
FundersScience and Engineering Research BoardMechanobiology Institute, SingaporeCentre National de la Recherche ScientifiqueFonds De La Recherche Scientifique - FNRSNational Natural Science Foundation of ChinaNational University of SingaporeChildren's Hospital FoundationNational Institutes of HealthStollery Children’s Hospital FoundationMedical Research CouncilHoward Hughes Medical InstituteNatural Sciences and Engineering Research Council of CanadaWomen and Children's Health Research InstituteNational Institute of General Medical SciencesChildren's Health Research InstituteEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentEuropean CommissionCanadian Institutes of Health ResearchVallee Foundation
KeywordsPolarity (international relations)BiologyCell polarityRelevance (law)PhenomenonCognitive sciencePerspective (graphical)NeuroscienceEvolutionary biologyEpistemologyCellComputer sciencePsychologyGeneticsPolitical science

Abstract

fetched live from OpenAlex

In this Perspective, Journal of Cell Science invited researchers working on cell and tissue polarity to share their thoughts on unique, emerging or open questions relating to their field. The goal of this article is to feature 'voices' from scientists around the world and at various career stages, to bring attention to innovative and thought-provoking topics of interest to the cell biology community. These voices discuss intriguing questions that consider polarity across scales, evolution, development and disease. What can yeast and protists tell us about the evolution of cell and tissue polarity in animals? How are cell fate and development influenced by emerging dynamics in cell polarity? What can we learn from atypical and extreme polarity systems? How can we arrive at a more unified biophysical understanding of polarity? Taken together, these pieces demonstrate the broad relevance of the fascinating phenomenon of cell polarization to diverse fundamental biological questions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.068
Threshold uncertainty score0.191

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.299
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes2
Has abstractyes

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