MétaCan
Menu
Back to cohort
Record W4392563074 · doi:10.1183/23120541.00976-2023

Transition of care from adolescence to early adulthood in severe asthmatic patients treated with omalizumab in real life

2024· article· en· W4392563074 on OpenAlexaboutno aff
Camille Taillé, Marc Humbert, Arnaud Bourdin, C. Thonnelier, A. Lajoinie, Jules Chassetuillier, Mathiéu Molimard, A. Deschildre

Bibliographic record

VenueERJ Open Research · 2024
Typearticle
Languageen
FieldHealth Professions
TopicAdolescent and Pediatric Healthcare
Canadian institutionsnot available
FundersNovartis
KeywordsMedicineOmalizumabYoung adultPediatricsEarly adulthoodIntensive care medicineGerontologyImmunologyImmunoglobulin EAntibody

Abstract

fetched live from OpenAlex

Transitional care consists of managing patients with chronic disease or disability from the pediatric to the adult care system [1–3]. It aims to prepare adolescents to manage their disease to become autonomous young adults, and to avoid any gap in the disease management. To succeed, transitional care must be an integral part of the management, coordinated by the healthcare team [3, 4]. However, to date, transition period remains critical in current practice, with a risk of loss to follow-up and deterioration in the health of adolescents with chronic conditions [5]. Footnotes This manuscript has recently been accepted for publication in the ERJ Open Research . It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article. Conflict of interest: Camille Taillé reports support for the present manuscript from Novartis. Payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Astrazeneca, Chiesi, GSK, Novartis, Sanofi, outside the submitted work. Conflict of interest: Arnaud Bourdin reports support for the present manuscript from Novartis. Payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Astrazeneca, Chiesi, GSK, Novartis, Sanofi, outside the submitted work. Conflict of interest: Antoine Deschildre reports support for the present manuscript from Novartis. Grants or contracts from Fondation du Souffle; Conseil Régional Hauts-de- France”- program 2014–2018 (grant number: ARCiR 2015–284), outside the submitted work; consulting fees from Novartis, ALK, GSK, Sanofi, Aimmune Therapeutics, DBV Technologies, Nestlé Health Science, Boehringer Ingelheim, outside the submitted work; Payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Novartis, ALK, GSK, Sanofi, Aimmune Therapeutics, DBV Technologies, Nestlé Health Science, Boehringer Ingelheim, outside the submitted work; Support for attending meetings and/or travel from ALK, Sanofi, Boehringer Ingelheim, Stallergenes Greer, Novartis, Astra-Zeneca, Meda, DBV Technologies, Aimmune, Nutricia, outside the submitted work. Participation on Data Safety Monitoring Board (DSMB) for BOOM study: BOOM study ClinicalTrials.gov identifier: [NCT04045301][1] Lead Investigator: Philippe Bégin (Montreal), outside the submitted work. Conflict of interest: Marc HUMBERT reports support for the present manuscript from Novartis. Consulting fees from Astrazeneca, Chiesi, GSK, Novartis, Sanofi, outside the submitted work. Payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Astrazeneca, GSK, Novartis, Sanofi, outside the submitted work. Conflict of interest: Audrey Lajoinie reports support for the present manuscript from Novartis. Conflict of interest: Mathieu Molimard reports support for the present manuscript from Novartis. Consulting fees from Novartis and Stallergen, outside the submitted work; Participation on a Data Safety Monitoring Board or Advisory Board for Banook, outside the submitted work. Conflict of interest: Céline Thonnelier reports support for the present manuscript from Novartis. [1]: /lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT04045301&atom=%2Ferjor%2Fearly%2F2024%2F02%2F15%2F23120541.00976-2023.atom

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.063
Threshold uncertainty score0.994

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.118
GPT teacher head0.478
Teacher spread0.360 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

Explore more

Same venueERJ Open ResearchSame topicAdolescent and Pediatric HealthcareFrench-language works237,207