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Record W4392734360 · doi:10.1016/j.cjca.2024.01.036

Vascular Aging in Women

2024· editorial· en· W4392734360 on OpenAlexaffvenue
Maria Agustina Lopez Laporte, Thais Coutinho

Bibliographic record

VenueCanadian Journal of Cardiology · 2024
Typeeditorial
Languageen
FieldMedicine
TopicCardiovascular Health and Disease Prevention
Canadian institutionsUniversity of Ottawa
Fundersnot available
KeywordsMedicine

Abstract

fetched live from OpenAlex

Well-established cardio-metabolic and sex-specific risk factors impact vascular health across a woman's lifespan and modulate lifelong risk for cardiovascular disease (CVD), which remains the number one killer of women worldwide. CVD remains under-studied and under-recognized in women. In this brief review, we describe the process of vascular aging, highlighting the impact of biological female sex and female sex hormones on arterial stiffening and endothelial dysfunction. We summarize the vasculo-protective effects of estrogen in premenopausal women, and explore the role of the menopausal transition and the autonomic nervous system on accelerated vascular aging seen in older women. Lastly, we will review the vascular impact of female-specific conditions, including polycystic ovarian syndrome and adverse pregnancy outcomes, such as preeclampsia.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Editorial · Consensus signal: none
Teacher disagreement score0.017
Threshold uncertainty score0.058

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0000.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0170.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.264
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2024
Admission routes2
Has abstractyes

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