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Record W4392811248 · doi:10.1097/sla.0000000000006267

Robotic Versus Laparoscopic Liver Resection in Various Settings

2024· article· en· W4392811248 on OpenAlexaff
Jasper P. Sijberden, Tijs J. Hoogteijling, Davit L. Aghayan, Francesca Ratti, Ek Khoon Tan, Victoria Morrison-Jones, Jacopo Lanari, Louis Haentjens, Kongyuan Wei, Stylianos Tzedakis, John B. Martinie, Daniel Osei Bordom, Giuseppe Zimmitti, Kaitlyn Crespo, Paolo Magistri, Nadia Russolillo, Simone Conci, Burak Görgeç, Andrea Benedetti Cacciaguerra, D.M. D'Souza, Gabriel Zozaya, Cèlia Caula, David A. Geller, Ricardo Robles Campos, Roland S. Croner, Shafiq Rehman, Elio Jovine, Михаил Ефанов, Adnan Alseidi, Riccardo Memeo, Ibrahim Dagher, Felice Giuliante, Ernesto Sparrelid, Jawad Ahmad, Tom Gallagher, Moritz Schmelzle, Rutger‐Jan Swijnenburg, Åsmund Avdem Fretland, Federica Cipriani, Ye Xin Koh, Steven A. White, Santi Lopez Ben, Fernando Rotellar, Pablo E. Serrano, Marco Vivarelli, Andrea Ruzzenente, Alessandro Ferrero, Fabrizio Di Benedetto, Marc G. Besselink, Iswanto Sucandy, Robert P. Sutcliffe, Dionisios Vrochides, David Fuks, Rong Liu, Mathieu D’Hondt, Umberto Cillo, Brian K. P. Goh, Luca Aldrighetti, Bjørn Edwin, Mohammad Abu Hilal

Bibliographic record

VenueAnnals of Surgery · 2024
Typearticle
Languageen
FieldMedicine
TopicHepatocellular Carcinoma Treatment and Prognosis
Canadian institutionsMcMaster University
FundersIntuitive SurgicalAstraZenecaBayerAmgen
KeywordsMedicinePerioperativePropensity score matchingSurgeryRetrospective cohort studyRobotic surgeryCohortResectionLaparoscopyGeneral surgeryInternal medicine

Abstract

fetched live from OpenAlex

OBJECTIVE: To compare the perioperative outcomes of robotic liver surgery (RLS) and laparoscopic liver surgery (LLS) in various settings. BACKGROUND: Clear advantages of RLS over LLS have rarely been demonstrated, and the associated costs of robotic surgery are generally higher than those of laparoscopic surgery. Therefore, the exact role of the robotic approach in minimally invasive liver surgery remains to be defined. METHODS: In this international retrospective cohort study, the outcomes of patients who underwent RLS and LLS for all indications between 2009 and 2021 in 34 hepatobiliary referral centers were compared. Subgroup analyses were performed to compare both approaches across several types of procedures: (1) minor resections in the anterolateral (2, 3, 4b, 5, and 6) or (2) posterosuperior segments (1, 4a, 7, 8), and (3) major resections (≥3 contiguous segments). Propensity score matching was used to mitigate the influence of selection bias. The primary outcome was textbook outcome in liver surgery (TOLS), previously defined as the absence of intraoperative incidents ≥grade 2, postoperative bile leak ≥grade B, severe morbidity, readmission, and 90-day or in-hospital mortality with the presence of an R0 resection margin in case of malignancy. The absence of a prolonged length of stay was added to define TOLS+. RESULTS: Among the 10.075 included patients, 1.507 underwent RLS and 8.568 LLS. After propensity score matching, both groups constituted 1.505 patients. RLS was associated with higher rates of TOLS (78.3% vs 71.8%, P < 0.001) and TOLS+ (55% vs 50.4%, P = 0.026), less Pringle usage (39.1% vs 47.1%, P < 0.001), blood loss (100 vs 200 milliliters, P < 0.001), transfusions (4.9% vs 7.9%, P = 0.003), conversions (2.7% vs 8.8%, P < 0.001), overall morbidity (19.3% vs 25.7%, P < 0.001), and microscopically irradical resection margins (10.1% vs. 13.8%, P = 0.015), and shorter operative times (190 vs 210 minutes, P = 0.015). In the subgroups, RLS tended to have higher TOLS rates, compared with LLS, for minor resections in the posterosuperior segments (n = 431 per group, 75.9% vs 71.2%, P = 0.184) and major resections (n = 321 per group, 72.9% vs 67.5%, P = 0.086), although these differences did not reach statistical significance. CONCLUSIONS: While both produce excellent outcomes, RLS might facilitate slightly higher TOLS rates than LLS.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.235
Threshold uncertainty score0.344

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.381
GPT teacher head0.344
Teacher spread0.037 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations80
Published2024
Admission routes1
Has abstractyes

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