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Record W4392871052 · doi:10.5114/fmpcr.2024.134702

The Systemic Immune-Inflammation Index (SII) and Neutrophil-Lymphocyte Ratio (NLR) are related to hospitalisation time in paediatric burn patients

2024· article· en· W4392871052 on OpenAlexaboutno aff
Agata Kawalec

Bibliographic record

VenueFamily Medicine & Primary Care Review · 2024
Typearticle
Languageen
FieldMedicine
TopicBurn Injury Management and Outcomes
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineNeutrophil to lymphocyte ratioInflammationSystemic inflammationImmunologyLymphocyteImmune system

Abstract

fetched live from OpenAlex

Background.The Systemic Immune-Inflammation Index (SII) and Neutrophil-Lymphocyte Ratio (NLR) are new markers of the immune response.There are few studies about the usefulness of these markers in the paediatric population with burns.Objectives.The aim of the study was to reveal the differences in the Systemic Immune-Inflammation Index (SII) and Neutrophil-Lymphocyte Ratio (NLR) in paediatric patients treated due to thermal burn. Material and methods.The study group consisted of 61 children (19 girls, 42 boys; mean age: 3.76; SD 4.79; min-max: 2 months -17 years of age) treated due to thermal burn in the Paediatric Surgery Department.Analysis of chosen complete blood cell count parameters (leucocytes -WBC; platelets -PLT; Systemic Immune-Inflammation Index -SII; Neutrophil-Lymphocyte Ratio -NLR) collected on the day of injury was used as biomarkers of inflammation in patients with and without wound cooling after injury.Results.Children with burns < 5 years of age who had higher PLT values on the day of admission (the day of injury) more frequently required surgical treatment (p = 0,027).Children with more extensive burn wounds (exceeding 10% TBSA) had higher WBC values on the day of the injury (p = 0.034).Higher NLR and SII values were related to longer hospitalisation (p < 0.05). Conclusions.The SII and NLR seem to be promising prognostic markers in children with burns.Further studies on larger groups are necessary to reveal the relationship of the new inflammatory markers with other aspects of burn injury in the paediatric population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.003
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.255
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2024
Admission routes1
Has abstractyes

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