Bibliographic record
Abstract
Abstract Skin involvement is common in all forms of histiocytic disorders and is seen in all ages. In general, for convenience, the histiocytoses were divided into those involving dendritic cells (DC disorders) and those involving the macrophage–monocyte lineage (or non‐DC disorders). Recent molecular insights, however, have led to a new classification system in which disorders that commonly harbour mutations in the MAPK pathway are classified together as the L group, while disorders that mainly involve skin and mucosa form the C group, the various forms of Rosai‐Dorfman disease constitute the R group, the malignant histiocytoses represent the M group, and finally the family of haemophagocytic lymphohistiocytoses comprise the H group. This chapter will provide an overview of the histiocytic disorders including a brief discussion of possible pathogenetic mechanisms, followed by an in‐depth discussion of the skin manifestations, pathology and therapy of the histiocytic disorders.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.036 | 0.026 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".