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Record W4393114568 · doi:10.35493/medu.44.20

Chronic Kidney Disease

2023· article· en· W4393114568 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueThe Meducator · 2023
Typearticle
Languageen
FieldMedicine
TopicRenal Diseases and Glomerulopathies
Canadian institutionsnot available
Fundersnot available
KeywordsKidney diseaseMedicineDiseaseIntensive care medicineInternal medicine

Abstract

fetched live from OpenAlex

Chronic kidney disease (CKD) is defined as low filtration function in the kidneys, protein in the urine, or functionally-important structural abnormalities. Low filtration function is associated with waste build-up in the bloodstream and difficulty in excreting salt and water, leading to fluid build-up. CKD may worsen over time, and some individuals with CKD may experience kidney failure, at which point dialysis or transplantation is required to replace kidney function. CKD may be caused by diabetes, renovascular disease, glomerulonephritis, polycystic kidney disease, and various genetic and environmental factors. In 2023, approximately four million Canadians live with and 11-13% of the global population are affected by CKD. This disorder has a 50% five-year mortality rate and is associated with lower quality of life compared to other chronic diseases, including sickle cell anemia, cancer, and cystic fibrosis. CKD’s comorbidities, such as diabetes, are increasing in prevalence and can increase the risk of developing CKD. Thus, the rates of CKD are also set to rise.3 Annual CKD management costs across Canada total $40 billion, with dialysis treatment for people with end-stage kidney disease (ESKD) costing $100,000 per patient.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.521
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.297
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it