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Record W4393153927 · doi:10.1101/2024.03.21.24304698

Disparity of secondary prevention among patients with rheumatic heart disease: A longitudinal study in Uganda

2024· preprint· en· W4393153927 on OpenAlexaff
Xinpeng Xu, Emily Chu, Hui Miao, Yuxian Du, Ryan Hoskins, Chinonso C. Opara, Neema W. Minja, Sarah Pickersgill, Jenifer Atala, Andrea Beaton, Rosemary Kansiime, Chris T. Longenecker, Miriam Nakitto, Emma Ndagire, Hadija Nalubwama, Emmy Okello, Rachel Sarnacki, Jafesi Pulle, David Watkins, Yanfang Su

Bibliographic record

VenuemedRxiv · 2024
Typepreprint
Languageen
FieldMedicine
TopicStreptococcal Infections and Treatments
Canadian institutionsCentre for Global Health ResearchUniversity of British Columbia
Fundersnot available
KeywordsSecondary preventionMedicineLongitudinal studyHeart diseaseDiseasePhysical therapyPediatricsInternal medicineEnvironmental healthIntensive care medicineGerontologyPathology

Abstract

fetched live from OpenAlex

Abstract Background Rheumatic heart disease (RHD) is most prevalent in socially disadvantaged settings, placing a severe burden on patients and their households. The study aims to investigate the disparity of healthcare costs, including financial and time costs, among RHD patients in Uganda. Methods We enrolled 54 RHD households from the Uganda National RHD Registry between June 2019 and February 2021. The patients were interviewed in baseline and 12-month follow-up surveys. A random-effect model was applied to examine the disparity of RHD financial and time costs. Our primary outcomes are the total outpatient costs for RHD patients’ most recent visit, consisting of direct medical costs, direct non-medical costs, and time costs. Results Following the COVID-19 pandemic, the total financial cost of outpatient visits for RHD patients increased by 9 USD on average ( P <0.01), with the change primarily driven by non-medical costs such as transportation and food (5.8 USD, P <0.05). Direct medical costs also increased significantly in the pandemic, with an average increase of 3.2 USD ( P <0.1). Compared with their counterparts, non-medical costs were higher for patients with poor infrastructure, with less education, who were older, and who were male. Patients with employment experienced a higher time cost than those without (3.3 hours, P <0.01). Conclusions The COVID-19 pandemic significantly increased RHD outpatient costs, mainly caused by the increase in non-medical costs. Our study implies that improving infrastructure, investing in education, and providing employees with time to seek care have the potential to reduce non-medical barriers to RHD secondary prevention.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score0.028

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.314
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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