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Record W4393214878 · doi:10.1101/2024.03.26.24304925

A protocol for a scoping review on the role of whole-body and dedicated body-part magnetic resonance imaging for assessment of adult and juvenile idiopathic inflammatory myopathies

2024· review· en· W4393214878 on OpenAlexaff
Mickael Essouma, Daniel Brito de Araújo, Jessica Day, Latika Gupta, Adina Kay Knight, Ann M. Reed, Elie Naddaf, Adriana Maluf Elias Sallum, Edoardo Marrani, Edoardo Conticini, Simone Appenzeller, Mazen M. Dimachkie, Tamima Mohamad Abou, Daren Gibson, Eva Kirkhus, Anneke J van der Koi, James B Lilleker, Matteo Lucchini, Pedro Machado, Mary Anne Riopel, Helga Sanner, Adam Schiffenbauer, Júlio Brandão Guimarães, Claudia Saad‐Magalhães, Susan O’Hanlon, Clarissa Harumi Omori, Susan Phaneuf, Siamak Moghadam‐Kia, Mirkamal Tolend, Iazsmin Bauer Ventura, Lisa G. Rider, Lisa Christopher‐Stine, Julie J. Paik, Brian M. Feldman, Samuel Katsuyuki Shinjo, Andréa S. Doria

Bibliographic record

VenuemedRxiv · 2024
Typereview
Languageen
FieldMedicine
TopicInflammatory Myopathies and Dermatomyositis
Canadian institutionsSickKids FoundationHospital for Sick ChildrenUniversity of Toronto
Fundersnot available
KeywordsJuvenileMagnetic resonance imagingMedicinePhysical medicine and rehabilitationRadiologyBiologyGenetics

Abstract

fetched live from OpenAlex

ABSTRACT Background Currently, there is lack of standardization of magnetic resonance imaging (MRI) scoring systems and protocols for assessment of idiopathic inflammatory myopathies (IIMs) in children and adults among treatment centres across the globe. Therefore, we will perform scoping reviews of the literature to inform available semi-quantitative and quantitative MRI scoring systems and protocols for the assessment and monitoring of skeletal muscle involvement in patients with IIMs with the final goal of providing evidence-based information for the future development of a universal standardized MRI scoring system in specific research and clinical settings in this population. Methods Electronic databases (PubMed, EMBASE, and Cochrane) will be searched to select relevant articles published from January 2000 to October 2023. Data will be synthesized narratively. Discussion This scoping review will extensively map evidence on the indications, utility for diagnosis and assessment of disease activity and damage using skeletal muscle MRI in IIMs. The results will allow the development of consensus recommendations for clinical practice and enable the standardization of research methods for MRI assessment of skeletal muscle changes in patients with IIMs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.101
metaresearch head score (Gemma)0.157
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.101
Threshold uncertainty score0.533

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1010.157
Meta-epidemiology (narrow)0.0050.004
Meta-epidemiology (broad)0.0130.016
Bibliometrics0.0250.020
Science and technology studies0.0050.005
Scholarly communication0.0080.009
Open science0.0050.007
Research integrity0.0100.007
Insufficient payload (model declined to judge)0.0860.013

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.358
Teacher spread0.329 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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