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Record W4393386859 · doi:10.1111/gcb.17227

How useful is genomic data for predicting maladaptation to future climate?

2024· article· en· W4393386859 on OpenAlexafffund
Brandon M. Lind, Rafael Candido‐Ribeiro, Pooja Singh, Mengmeng Lu, Dragana Obreht Vidaković, Tom R. Booker, Michael C. Whitlock, Sam Yeaman, Nathalie Isabel, Sally N. Aitken

Bibliographic record

VenueGlobal Change Biology · 2024
Typearticle
Languageen
FieldEnvironmental Science
TopicSpecies Distribution and Climate Change
Canadian institutionsUniversité LavalNatural Resources CanadaUniversity of CalgaryCanadian Forest ServiceUniversity of British Columbia
FundersNatural Sciences and Engineering Research Council of CanadaGenome AlbertaAlberta Innovates Bio SolutionsUniversity of British ColumbiaGenome British ColumbiaUniversity of AlbertaGénome QuébecCompute Canada
KeywordsMaladaptationClimate changeOffset (computer science)PopulationEcologyGeographyComputer scienceBiologyDemography

Abstract

fetched live from OpenAlex

Abstract Methods using genomic information to forecast potential population maladaptation to climate change or new environments are becoming increasingly common, yet the lack of model validation poses serious hurdles toward their incorporation into management and policy. Here, we compare the validation of maladaptation estimates derived from two methods—Gradient Forests (GF offset ) and the risk of non‐adaptedness (RONA)—using exome capture pool‐seq data from 35 to 39 populations across three conifer taxa: two Douglas‐fir varieties and jack pine. We evaluate sensitivity of these algorithms to the source of input loci (markers selected from genotype–environment associations [GEA] or those selected at random). We validate these methods against 2‐ and 52‐year growth and mortality measured in independent transplant experiments. Overall, we find that both methods often better predict transplant performance than climatic or geographic distances. We also find that GF offset and RONA models are surprisingly not improved using GEA candidates. Even with promising validation results, variation in model projections to future climates makes it difficult to identify the most maladapted populations using either method. Our work advances understanding of the sensitivity and applicability of these approaches, and we discuss recommendations for their future use.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.456
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.318
Teacher spread0.214 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations57
Published2024
Admission routes2
Has abstractyes

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