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Record W4393562047 · doi:10.1117/12.3006245

Multistream fusion segmentation and classification of prostate lesions from magnetic resonance images

2024· article· en· W4393562047 on OpenAlexaff
Rongfeng Wei, Wenxu Zhang, Weixuan Kou, Cristian Rey, Harry Marshall, Bernard Chiu

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicProstate Cancer Diagnosis and Treatment
Canadian institutionsWilfrid Laurier University
Fundersnot available
KeywordsProstate cancerSegmentationComputer scienceProstateMagnetic resonance imagingArtificial intelligencePattern recognition (psychology)Modality (human–computer interaction)Image segmentationLesionDiffusion MRIClassifier (UML)MedicineRadiologyCancerPathology

Abstract

fetched live from OpenAlex

Prostate cancer is a significant contributor to cancer-related deaths in men. Detecting prostate cancer early can greatly increase the likelihood of successful treatment. However, detecting and assessing prostate lesions from multiparametric magnetic resonance images (MRI) is time-consuming and variable across radiologists with different levels of experience. We present an integrated framework for segmenting and classifying prostate lesions from MRI. The proposed approach is in contrast with most existing automated prostate analysis approaches, which treat segmentation and classification of prostate lesions as two separate tasks with no interactions between them. In the proposed framework, preliminary lesion boundaries were first segmented from T2-weighted (T2W) and diffusion-weighted images (DWI) by a three-stream network. The region of interest (ROI) enclosing the segmented lesion was fed to a weakly supervised classification network, which predicted the Gleason grade of the lesion and provided the class activation maps (CAMs) corresponding to multiple MRI modalities. Finally, MR images of different modalities with the corresponding CAMs were fed to a six-stream network to generate an enhanced lesion mask. Our experiments showed that CAMs generated by the proposed weakly supervised classifier improved segmentation performance. Our proposed method has a great potential to improve the accuracy and efficiency of prostate MRI interpretation workflow.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.006
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.297
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2024
Admission routes1
Has abstractyes

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