Cytomegalovirus Colitis in an Immunocompetent Patient Following COVID-19
Bibliographic record
Abstract
Colitis due to cytomegalovirus (CMV) in immunocompetent patients is an infrequent occurrence and is associated with medical conditions that cause immunodepression, such as diabetes mellitus, prolonged residence in the intensive care unit, autoimmune diseases, organ failure, etc. The immune imbalance noticed in patients with severe coronavirus disease 2019 (COVID-19) can lead to co-infection or reactivation of CMV. But CMV colitis following a recent COVID-19 is extremely rare. We present a case of an elderly female, who recently had COVID-19 and was evaluated for nausea vomiting and abdominal pain. Colonoscopy showed severe inflammation and congested mucosa and histopathological analysis of the biopsy specimen confirmed the diagnosis of CMV colitis. The patient had an excellent response to oral ganciclovir therapy. This case highlights the importance of suspecting CMV colitis in patients with recent COVID-19 presenting with nonspecific symptoms, such as in our case of nausea, vomiting, and abdominal pain and pancolitis on imaging, as early diagnosis is the key to improved outcomes. Clin Infect Immun. 2024;9(1):25-30 doi: https://doi.org/10.14740/cii177
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.002 | 0.002 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".