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Record W4394045882 · doi:10.5281/zenodo.8008077

CFdb: interactomes

2023· dataset· en· W4394045882 on OpenAlexaff
Michael A. Skinnider

Bibliographic record

VenueZenodo (CERN European Organization for Nuclear Research) · 2023
Typedataset
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBioinformatics and Genomic Networks
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsComputer scienceComputational biologyBiology

Abstract

fetched live from OpenAlex

This upload contains predicted interactomes for 23 species derived from meta-analysis of co-fractionation mass spectrometry (CF-MS) data. The following individual organisms are represented: Arabidopsis thaliana Brassica oleracea Caenorhabditis elegans Chaetomium thermophilum Chlamydomonas reinhardtii Dictyostelium discoideum Drosophila melanogaster Glycine max Homo sapiens Mus musculus Nematostella vectensis Oryza sativa Plasmodium berghei Plasmodium falciparum Plasmodium knowlesi Saccharomyces cerevisiae Strongylocentrotus purpuratus Triticum aestivum Trypanosoma brucei Xenopus laevis Escherichia coli Anabaena sp. PCC 7120 Synechocystis sp. PCC 6803 Network inference was performed by training a random forest classifier on known complexes (from CORUM or EcoCyc, for eukaryotes and prokaryotes respectively) to predict interacting protein pairs in cross-validation. Files include the complete classifier scores for every possible protein pair, sorted in descending order. The resulting networks can then be thresholded at an arbitrary precision.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.076
Threshold uncertainty score0.253

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0040.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0060.007
Science and technology studies0.0010.000
Scholarly communication0.0030.002
Open science0.0030.003
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0760.087

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.252
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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